ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021
Mobile Colistin Resistance Enzyme MCR-3 Facilitates Bacterial Evasion of Host Phagocytosis.
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In one paragraph
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Fitness costs of mobilised colistin resistance gene 3 (mcr-3): systematic review, epidemiological study, and functional analysis.EBioMedicine · 2025Pooled it
- Genomic characterization of non-fermenting gram-negative bacilli with metallo beta lactamase production and mcr based colistin resistance causing soft tissue infections: a seven-year hospital based prospective cross-sectional study.Molecular biology reports · 2026Article
- Molecular epidemiology of levofloxacin-resistantMicrobiology spectrum · 2026Article
- Macrophage-mediated antibiotic evasion and competitive dominance of mcr-3-carrying Escherichia coli.PLoS pathogens · 2026Article
- Targeting MCR-3 and membrane biosynthesis: mechanistic insights into pterostilbene-colistin synergy.Microbiology spectrum · 2026Article
- The Gut Microbiome and Colistin Resistance: A Hidden Driver of Antimicrobial Failure.International journal of molecular sciences · 2025Review
- Silver nitrate enhances antibacterial effect of colistin against intrinsic colistin resistantFrontiers in veterinary science · 2025Article
- Irisin alleviated sepsis via enhancing macrophage phagocytosis and reducing inflammation levels.Frontiers in immunology · 2025Article
- Site-selective modifications by lipid A phosphoethanolamine transferases linked to colistin resistance and bacterial fitness.mSphere · 2024Article
- The multifaceted roles of phosphoethanolamine-modified lipopolysaccharides: from stress response and virulence to cationic antimicrobial resistance.Microbiology and molecular biology reviews : MMBR · 2024Review
- Guanethidine Enhances the Antibacterial Activity of Rifampicin Against Multidrug-Resistant Bacteria.Microorganisms · 2024Article
- Review
- Correlation Analysis of the Transcriptome and Gut Microbiota inMicroorganisms · 2024Article
- The Effect of the PhoP/PhoQ System on the Regulation of Multi-Stress Adaptation Induced by Acid Stress inFoods (Basel, Switzerland) · 2024Article
- The synergistic antibacterial activity and mechanism of colistin-oxethazaine combination against gram-negative pathogens.Frontiers in pharmacology · 2024Article
- Inactivation of MST1/2 Controls Macrophage Polarization to Affect Macrophage-Related Disease via YAP and Non-YAP Mechanisms.International journal of biological sciences · 2024Article
- In Situ Neutralization and Detoxification of LPS to Attenuate Hyperinflammation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Phosphoethanolamine Transferases as Drug Discovery Targets for Therapeutic Treatment of Multi-Drug Resistant Pathogenic Gram-Negative Bacteria.Antibiotics (Basel, Switzerland) · 2023Review
- Article
- The Impact of Colistin Resistance on the Activation of Innate Immunity by Lipopolysaccharide Modification.Infection and immunity · 2023Article
Corrections and comments
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Authors and funding
17 authors at 8 institutions in 2 countries.
Wenjuan YinBeijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Zhuoren LingBeijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Yanjun DongDepartment of Basic Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Haidian, Beijing, 100193, China.
Lu QiaoBeijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Yingbo ShenCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, 100101, China.
Zhihai LiuBeijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Yifan WuBeijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Wan LiBeijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Rong ZhangThe Second Affiliated Hospital of Zhejiang University, Zhejiang University, Hangzhou, 310009, China.
Timothy R WalshDepartment of Zoology, University of Oxford, Oxford, OX1 3SZ, UK.
Chongshan DaiBeijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Juan LiState Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, 102206, China.
Hui YangNHC Key Laboratory of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment, No. 7 Panjiayuan Nanli, Beijing, 100021, China.
Dejun LiuBeijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Yang WangBeijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.ORCID 0000-0002-5928-9377
George Fu GaoCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, 100101, China.
Jianzhong ShenBeijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Beijing University of Agriculture · CNChinese Academy of Sciences · CNChina Agricultural University · CNChina National Center for Food Safety Risk Assessment · CNNational Institute for Communicable Disease Control and Prevention · CNQingdao Agricultural University · CNSecond Affiliated Hospital of Zhejiang University · CNUniversity of Oxford · GB
Funding
111 Project B20013Guangdong Major Project of Basic and Applied Basic Research 2020B0301030007Medical Research Council MR/S013768/2National Key Research and Development Program of China 2018YFD0500300National Natural Science Foundation of China 81861138051National Natural Science Foundation of China 81861138052National Natural Science Foundation of China 81861138053UK Medical Research Council MR/S013768/1
Abstract
Mobile colistin resistance enzyme MCR-3 is a phosphoethanolamine transferase modifying lipid A in Gram-negative bacteria. MCR-3 generally mediates low-level (≤8 mg L
Indexed as
Aeromonas salmonicidaAnimalsAnti-Bacterial AgentsColistinDrug Resistance, BacterialEscherichia coliFemaleGenes, BacterialMiceMice, Inbred BALB CMicrobial Sensitivity TestsPhagocytosisAnti-Bacterial AgentsColistincolistinlipid A modificationmcr-3phagocytosisvirulence
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.