Evidence map›Paper›PMID 34323340›Full record

ArticleEuropean journal of cancer care2021

Psychological predictors of chemotherapy-induced nausea in women with breast cancer: Expectancies and perceived susceptibility.

Elise J Devlin, Hayley S Whitford, Anita R Peoples, Gary R Morrow, Sreedhar Katragadda, Jeffrey K Giguere, Bilal Naqvi, Joseph Roscoe

Open access · greenAbstract read
In one paragraph

Article in European journal of cancer care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Elise J DevlinSchool of Psychology, The University of Adelaide, Adelaide, South Australia, Australia.ORCID https://orcid.org/0000-0001-7459-8613
Hayley S WhitfordSchool of Psychology, The University of Adelaide, Adelaide, South Australia, Australia.
Anita R PeoplesDepartment of Surgery, University of Rochester Medical Center, Rochester, New York, USA.ORCID https://orcid.org/0000-0003-3645-3960
Gary R MorrowDepartment of Surgery, University of Rochester Medical Center, Rochester, New York, USA.
Sreedhar KatragaddaSoutheast Clinical Oncology Research Consortium, Winston Salem, North Carolina, USA.
Jeffrey K GiguereNCORP of the Carolinas (Greenville Health System), Greenville, South Carolina, USA.
Bilal NaqviWisconsin NCI Community Oncology Research Program, Marshfield, Wisconsin, USA.
Joseph RoscoeDepartment of Surgery, University of Rochester Medical Center, Rochester, New York, USA.
The University of Adelaide · AUUniversity of Rochester Medical Center · USMarshfield Clinic · USPrisma Health · USSoutheast Clinical Oncology Research Consortium · USUniversity of Utah · US

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Cancer Control Research Training Curriculum (R25T)R25CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI JANELSINS, MICHELLE C, MORROW, GARY R · 2004 to 2018
$6.7M
Clinical and Translational Cancer Control Research Training ProgramT32CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, Gary R Morrow · 2019 to 2026
$2.7M
NCI NIH HHS R25 CA102618NCI NIH HHS T32 CA102618NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

objectiveChemotherapy-induced nausea is challenging to predict and treat. Research indicates that pretreatment psychological variables including patients' perceptions of their susceptibility to nausea, expectancies of treatment-related nausea and nausea history (i.e., motion sickness, morning sickness and baseline levels of nausea) may aid in predicting nausea severity during chemotherapy. However, this research is dated and limited in quantity. We investigated whether psychological variables could improve prediction of nausea severity to inform interventions targeting chemotherapy-induced nausea.

methodsIn this secondary analysis, a subgroup of women receiving chemotherapy (for the first time) for breast cancer completed pretreatment measures: perceived nausea susceptibility, nausea expectancies, nausea history and baseline nausea. They rated subsequent nausea severity across 4-days, during treatment and posttreatment in a self-report diary. Structural Equation Modelling was used to explore associations.

resultsAcross the women (N = 481), perceived nausea susceptibility predicted subsequent nausea severity (β = 0.16), but nausea expectancies did not (β = 0.05). Nausea history variables demonstrated small-moderate associations with perceived susceptibility (β = 0.21-0.32) and negligible-small associations with nausea expectancies (β = 0.07-0.14).

conclusionPerceived nausea susceptibility appears to capture patients' nausea history, to a degree, and is related to nausea severity during treatment. This is an important variable to include in pretreatment prediction of patients at risk of severe nausea.

Indexed as

Antineoplastic AgentsBreast NeoplasmsFemaleHumansNauseaPregnancySelf ReportVomitingAntineoplastic Agentschemotherapyexpectnauseanocebopath analysissusceptibility

Identifiers

PMID34323340
PMCPMC9022467
OpenAlexW3186589128

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.