SynthesisTechnology in cancer research & treatment
Prognostic Value of Bleeding in Gastrointestinal Stromal Tumors: A Meta-Analysis.
Synthesis in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Endoscopic Hemostasis for Gastrointestinal Stromal Tumor Hemorrhage: A Case Series and Retrospective Analysis of Risk Factors.DEN open · 2026Article
- Intratumoral and Peritumoral Radiomics based on Contrast-enhanced CT Images: Biomarkers to Predict the Risk-Grade of Gastrointestinal Stromal TumorsCurrent medical imaging · 2026Article
- An incidental finding of duodenal gastrointestinal stromal tumor (dGIST): a case report.Annals of medicine and surgery (2012) · 2026Article
- Unraveling the site-specific features in small intestinal stromal tumors: a retrospective study.BMC gastroenterology · 2025Article
- Gastrointestinal stromal tumor of the duodenum presenting with shock and massive upper and lower gastrointestinal bleeding: a case report and review of the literature.Journal of medical case reports · 2024Review
- Duodenal gastrointestinal stromal tumor presenting with life-threatening upper GI bleeding in a young patient: A case report and literature review.Clinical case reports · 2024Article
- Factors associated with gastrointestinal stromal tumor rupture and pathological risk: A single-center retrospective study.World journal of radiology · 2023Article
- Coexistence of small gastrointestinal stromal tumor and pancreatic cancer: A case report and literature review.Oncology letters · 2023Article
- Jejunal Gastrointestinal Stromal Tumor: A Strange Cause of Massive Gastrointestinal Bleeding.Cureus · 2023Article
- Jejunal gist simulating a uterine myoma: A case report.International journal of surgery case reports · 2023Article
- A jejunal gastrointestinal stromal tumor with massive gastrointestinal hemorrhage treated by emergency surgery: A case report.Medicine · 2022Article
- Article
- A case report of gastrointestinal stromal tumor of the duodenum.American journal of translational research · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGastrointestinal bleeding is the most common clinical manifestation of gastrointestinal stromal tumor. It is of great significance to the prognosis of patients. But the results are controversial. The purpose of this study was to evaluate the relationship between gastrointestinal bleeding and clinical prognosis in patients with GIST.
methodsA systematic literature search was performed in Pumbed, Cochrane Library, EMBASE, ClinicalTrials.gov, CNKI, VIP and wanfang databases with the pattern of unlimited languages. 12 studies with 2781 individuals were included in the final analysis. The overall survival (OS), recurrence-free survival/disease-free survival (RFS/DFS) and related factors affecting bleeding in patients with gastrointestinal stromal tumor (GIST) were extracted. Hazard ratio (HR) and 95% confidence interval (CI) were used for in the meta-analysis.
resultsA total of 12 articles were included in the study, including 2781 patients with GIST, including 845 patients with gastrointestinal bleeding. The OS of GIST patients with gastrointestinal bleeding was significantly worse (HR = 2.54, 95% CI = 1.13-5.73,
conclusionsThe OS of GIST patients with GI bleeding was worse than non-GI bleeding, but had no significant effect on RFS. Nevertheless the aging factor, the location of GIST in the small intestine, tumor diameter ≥ 5 cm, Mitotic index ≥ 5/50 HPF and tumor rupture all increased the risk of GI bleeding in patients with GIST.
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