Evidence map›Paper›PMID 34323107›Full record

ArticleJournal of dental research2021

Biomineralization of Dental Tissues Treated with Silver Diamine Fluoride.

R M Sulyanto, M Kang, S Srirangapatanam, M Berger, F Candamo, Y Wang, J R Dickson, M W Ng, S P Ho

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Silver diamine fluoride for non-operative restorative treatment and prevention of dental caries.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2026
    Review
  3. Knowledge and attitudes regarding silver diamine fluoride among Brazilian dentists: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Silver diamine fluoride differentially affects dentin and hypomineralized enamel permeabilities.Dental materials : official publication of the Academy of Dental Materials · 2025
    Article
  9. Review
  10. Article
  11. Cariostatic Agents: From Silver Diamine Fluoride to Emerging Bioactive Compounds.Clinical, cosmetic and investigational dentistry · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Interface between Materials and Oral Biology.Journal of dental research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

R M SulyantoDepartment of Dentistry, Boston Children's Hospital, Boston, MA, USA.
M KangDepartment of Preventive and Restorative Dental Sciences, School of Dentistry, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-3188-4481
S SrirangapatanamDepartment of Preventive and Restorative Dental Sciences, School of Dentistry, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-9179-3573
M BergerDepartment of Dentistry, Boston Children's Hospital, Boston, MA, USA.
F CandamoDepartment of Developmental Biology, Harvard School of Dental Medicine, Boston, MA, USA.
Y WangDepartment of Preventive and Restorative Dental Sciences, School of Dentistry, University of California San Francisco, San Francisco, CA, USA.
J R DicksonDepartment of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
M W NgDepartment of Dentistry, Boston Children's Hospital, Boston, MA, USA.
S P HoDepartment of Preventive and Restorative Dental Sciences, School of Dentistry, University of California San Francisco, San Francisco, CA, USA.
University of California, San Francisco · USBoston Children's Hospital · USHarvard University · US

Funding

Load-mediated Adaptation of the Bone-PDL-Tooth Complex in VertebratesR01DE022032 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HO, SUNITA P · 2012 to 2021
$3.4M
NIDCR NIH HHS R01 DE022032
6 · The paper itself

Abstract

Silver diamine fluoride (SDF) is a dental biomaterial used to arrest dental caries. To better understand SDF's mechanism of action, we examined the localization of silver within the tissues of SDF-treated teeth. Carious primary teeth fixed within 2 min of SDF application (SDF-minutes,

Indexed as

Dental CariesBiomineralizationCariostatic AgentsDentinFluorides, TopicalHumansQuaternary Ammonium CompoundsSilver CompoundsCariostatic AgentsFluorides, TopicalQuaternary Ammonium CompoundsSilver Compoundssilver diamine fluoridecariesmetalloproteaseprimary toothtertiary dentintrace metalszinc

Identifiers

PMID34323107
PMCPMC8381688
OpenAlexW3186619303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.