ArticleJournal of veterinary internal medicine2021
The association between single nucleotide polymorphism in vitamin D receptor and calcium oxalate urolithiasis in dogs.
Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Serum 25-hydroxyvitamin D concentrations in dogs with coccidioidomycosis and variables associated with extent of clinically evident disease.Journal of veterinary internal medicine · 2023Article
- Characterization of the urogenital microbiome in Miniature Schnauzers with and without calcium oxalate urolithiasis.Journal of veterinary internal medicine · 2022Article
- The association between single nucleotide polymorphism in vitamin D receptor and calcium oxalate urolithiasis in dogs.Journal of veterinary internal medicine · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPolymorphisms of the vitamin D receptor (VDR) are associated with calcium oxalate (CaOx) nephrolithiasis in humans.
objectivesTo investigate the association between VDR polymorphisms and susceptibility to CaOx urolithiasis in dogs. ANIMALS: Thirty-five dogs with CaOx urolithiasis were compared with 40 stone-free dogs.
methodsThis was a case-control study. Two VDR gene polymorphisms (rs851998024 and rs852900542) were detected by specific TaqMan real-time polymerase chain reaction assay, and their relationship with serum 1,25-dihydroxyvitamin D, serum and urinary electrolyte concentrations was evaluated.
resultsThe distribution of the rs852900542 polymorphism was significantly different between the case and the control dogs (x CONCLUSIONS AND CLINICAL IMPORTANCE: This finding suggests that vitamin D metabolism might play a role in CaOx stone formation in dogs.
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Registered trials
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