Observational studyInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2022
Differences in the neutrophil/lymphocyte ratio and the platelet/lymphocyte ratio in pregnant women with and without COVID-19.
Observational study in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Comparative analysis of COVID-19 pneumonia in pregnant versus matched non-pregnant women: radiologic, laboratory, and clinical perspectives.Scientific reports · 2024Article
- Can the neutrophil-to-lymphocyte ratio be used as an early marker of small fetuses for gestational age? A prospective study.Frontiers in medicine · 2024Article
- Predicting Potentially Fatal COVID-19 Disease in Pregnant Patients Using the Neutrophil-to-Lymphocyte Ratio (NLR).Journal of clinical medicine · 2023Article
- Clinical and laboratory characteristics of COVID-19 in pregnant women.Journal of medicine and life · 2023Article
- Neutrophil/Lymphocyte and Platelet/Lymphocyte Ratio in Preterm Premature Rupture of Membranes.Cureus · 2023Article
- Correlation of systemic inflammation biomarkers and disease severity in pregnant women with COVID-19.Revista da Associacao Medica Brasileira (1992) · 2023Article
- The Predictive Role of Maternal Biological Markers and Inflammatory Scores NLR, PLR, MLR, SII, and SIRI for the Risk of Preterm Delivery.Journal of clinical medicine · 2022Article
- Differences in the neutrophil/lymphocyte ratio and the platelet/lymphocyte ratio in pregnant women with and without COVID-19.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022Observational
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Authors and funding
2 authors.
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Abstract
objectiveTo determine the differences in the neutrophil/lymphocyte ratio (NLR) and the platelet/lymphocyte ratio (PLR) in pregnant women with and without COVID-19.
methodsObservational, cross-sectional, retrospective, comparative, open, controlled study done from January to April 2021 at the UMAE Hospital de Gineco Obstetricia "Luis Castelazo Ayala" Instituto Mexicano del Seguro Social. Mexico City, Mexico: Patients were divided into those with a negative test for COVID-19 and those with a positive test, with the latter then being divided according to disease severity into mild, moderate, and severe groups. In all the NLR and PLR were calculated. Symptoms, vital signs, and oxygen saturation were documented. STATISTICAL ANALYSIS: Central tendency and dispersion measures, Kruskal-Wallis test, Mann-Whitney U test, and chi-squared test were used. Sensitivity, specificity, positive predictive value, negative predictive value, and odds ratio (OR) were calculated.
resultsSeventy-seven patients were included, 24 without COVID-19 and 53 with COVID-19. There were 33, 10, and 10 patients in the mild, moderate, and severe disease groups, respectively. There was no difference in NLR between the groups and the PLR was significantly higher in the severe disease group. With a 5.1 NLR cutoff point, between normal and those with severe disease, the sensitivity was 70% and specificity 63%, whilst with a 221 PLR cutoff point, the sensitivity was 90% and the specificity 83% (OR 45, 95% CI 4.40-461.7).
conclusionPLR more than NLR was useful to detect pregnant patients with COVID-19 with severe disease.
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