Evidence map›Paper›PMID 34322672›Full record

ArticleAdvanced genetics (Hoboken, N.J.)2021

The molecular underpinnings of fertility: Genetic approaches in

Xue Mei, Andrew W Singson

Open access · goldAbstract read
In one paragraph

Article in Advanced genetics (Hoboken, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Fertility reversibly modulatesbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Where are all the egg genes?Frontiers in cell and developmental biology · 2023
    Review
  6. Large-scale sampling ofmicroPublication biology · 2023
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xue MeiDepartment of Genetics, Waksman Institute, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Andrew W SingsonDepartment of Genetics, Waksman Institute, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Rutgers, The State University of New Jersey · US

Funding

[RNW] - Gamete Interactions in Caenorhabditis elegansR01HD054681 · NICHD · RUTGERS, THE STATE UNIV OF N.J. · PI ANDREW W. SINGSON · 2008 to 2026
$5.3M
NICHD NIH HHS R01 HD054681
6 · The paper itself

Abstract

The study of mutations that impact fertility has a catch-22. Fertility mutants are often lost since they cannot simply be propagated and maintained. This has hindered progress in understanding the genetics of fertility. In mice, several molecules are found to be required for the interactions between the sperm and egg, with JUNO and IZUMO1 being the only known receptor pair on the egg and sperm surface, respectively. In

Indexed as

C. eleganseggfertilityfertilizationforward genetic screensmutantsreproductionsperm

Identifiers

PMID34322672
PMCPMC8315475
OpenAlexW3095948499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.