Evidence map›Paper›PMID 34322533›Full record

ArticleFrontiers in veterinary science2021

Cultured Horse Articular Chondrocytes in 3D-Printed Chitosan Scaffold With Hyaluronic Acid and Platelet Lysate.

Elena De Angelis, Roberta Saleri, Paolo Martelli, Lisa Elviri, Annalisa Bianchera, Carlo Bergonzi, Marta Pirola, Roberta Romeo, Melania Andrani, Valeria Cavalli and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Elena De AngelisDepartment of Veterinary Science, University of Parma, Parma, Italy.
Roberta SaleriDepartment of Veterinary Science, University of Parma, Parma, Italy.
Paolo MartelliDepartment of Veterinary Science, University of Parma, Parma, Italy.
Lisa ElviriFood and Drug Department, University of Parma, Parma, Italy.
Annalisa BiancheraFood and Drug Department, University of Parma, Parma, Italy.
Carlo BergonziFood and Drug Department, University of Parma, Parma, Italy.
Marta PirolaDepartment of Veterinary Science, University of Parma, Parma, Italy.
Roberta RomeoDepartment of Veterinary Science, University of Parma, Parma, Italy.
Melania AndraniDepartment of Veterinary Science, University of Parma, Parma, Italy.
Valeria CavalliDepartment of Veterinary Science, University of Parma, Parma, Italy.
Virna ContiDepartment of Veterinary Science, University of Parma, Parma, Italy.
Ruggero BettiniFood and Drug Department, University of Parma, Parma, Italy.
Benedetta PasseriDepartment of Veterinary Science, University of Parma, Parma, Italy.
Francesca RavanettiDepartment of Veterinary Science, University of Parma, Parma, Italy.
Paolo BorghettiDepartment of Veterinary Science, University of Parma, Parma, Italy.
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D) printing has gained popularity in tissue engineering and in the field of cartilage regeneration. This is due to its potential to generate scaffolds with spatial variation of cell distribution or mechanical properties, built with a variety of materials that can mimic complex tissue architecture. In the present study, horse articular chondrocytes were cultured for 2 and 4 weeks in 3D-printed chitosan (CH)-based scaffolds prepared with or without hyaluronic acid and in the presence of fetal bovine serum (FBS) or platelet lysate (PL). These 3D culture systems were analyzed in terms of their capability to maintain chondrocyte differentiation

Indexed as

biomaterialscartilagechitosanchondrocyteshyaluronic acidplatelet lysatetissue engineering

Identifiers

PMID34322533
PMCPMC8311290
OpenAlexW3178028502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.