Evidence map›Paper›PMID 34322448›Full record

ArticleJournal of family medicine and primary care2021

When the head is big, think this too: Megalencephalic leukoencephalopathy in a toddler with only a large head. A case report.

Shyam Chandrasekar, Joseph John, Amit K Satapathy, Samarendra Mahapatro

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of family medicine and primary care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shyam ChandrasekarDepartment of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Joseph JohnDepartment of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Amit K SatapathyDepartment of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Samarendra MahapatroDepartment of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
All India Institute of Medical Sciences Bhubaneswar · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a one-year old, developmentally normal toddler from a non Agarwal community, who presented to us with only a large head. The examination findings were unremarkable except a large head circumference. Neuroimaging confirmed the diagnosis of megalencephalic leukoencephalopathy (MLC). Although developmental delay and seizures are common manifestations in MLC, we want to highlight the fact that many children like ours may have no neurological manifestations at all which makes it necessary to do neuroimaging to establish the diagnosis and offer genetic testing for confirmation of the same.

Indexed as

Cystsdemyelinationdevelopmental disabilitieshereditary central nervous system demyelinating diseasesmegalencephalyVan der Knaap diseasewhite matter

Identifiers

PMID34322448
PMCPMC8284232
OpenAlexW3181956144

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.