Evidence map›Paper›PMID 34322379›Full record

ArticleFrontiers in oncology2021

Long Non-Coding RNA LINC01410 Promoted Tumor Progression

Lili Lu, Shilong Zhang, Zhengqing Song, Weiqi Lu, Zhiming Wang, Yuhong Zhou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lili LuBiotherapy Centre, Zhongshan Hospital, Fudan University, Shanghai, China.
Shilong ZhangDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhengqing SongDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, China.
Weiqi LuDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhiming WangDepartment of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai, China.
Yuhong ZhouBiotherapy Centre, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhongshan Hospital · CNFudan University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLong non-coding RNAs (lncRNAs) have been recently emerging as crucial molecules in multiple human cancers. However, their expression patterns, roles as well as the underlying mechanisms in gallbladder cancer (GBC) remain largely unclear. MATERIALS AND

methodsThe expression of lncRNAs in GBC was downloaded from GEO database. Quantitative real-time polymerase chain reaction (qRT-PCR) and RNA

resultsLINC01410 was significantly upregulated in the GBC tissues compared to adjacent non-tumor tissues. High LINC01410 expression was significantly associated with poor prognosis of GBC patients. We identified LINC01410 to be 2,877 bp in length and mainly localized in the cytoplasm of GBC cells. Overexpression of LINC01410 promoted GBC cell proliferation, migration, and invasion

conclusionsOur results suggested that LINC01410 was an important lncRNA that promoted GBC progression

Indexed as

gallbladder cancerLINC01410long non-coding RNAoncogeneSTAT5

Identifiers

PMID34322379
PMCPMC8312242
OpenAlexW3181966292

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.