Evidence map›Paper›PMID 34322213›Full record

ArticleDental research journal2021

Antibacterial effectiveness of diluted preparations of intracanal medicaments used in regenerative endodontic treatment on dentin infected by bacterial biofilm: An

Mehrfam Khoshkhounejad, Mohammadreza Sharifian, Hadi Assadian, Mahsa Sobhi Afshar

Open access · goldAbstract read
In one paragraph

Article in Dental research journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. ComparativePeerJ · 2026
    Article
  2. PeerJ · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mehrfam KhoshkhounejadDepartment of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Mohammadreza SharifianDepartment of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Hadi AssadianDepartment of Endodontics, School of Dentistry, Shahed University, Tehran, Iran.
Mahsa Sobhi AfsharDepartment of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRShahed University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConventional drug mixtures used in regenerative endodontic procedures have a toxic effect and no consensus has been reached about their best composition and concentration. Therefore, the aim of this study was to determine minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum biofilm inhibitory concentration (MBIC) of the antimicrobial preparations and to compare their antimicrobial efficacy on bovine dentin infected by MATERIALS AND

methodsFor this original

resultsAll medicament groups significantly showed an antimicrobial efficacy compared with negative control (without antibiotic) (

conclusionTAP, DAP, co-amoxiclav, and CH (at its MBC value) could effectively eliminate biofilm bacteria on the dentin surface. Antimicrobial efficacy of other medicaments containing cefaclor or clindamycin was limited.

Indexed as

BiofilmsEnterococcus faecalisregenerative endodontics

Identifiers

PMID34322213
PMCPMC8314970
OpenAlexW3171739084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.