Evidence map›Paper›PMID 34322135›Full record

ArticleFrontiers in immunology2021

Anti-Microbiota Vaccines Modulate the Tick Microbiome in a Taxon-Specific Manner.

Lourdes Mateos-Hernández, Dasiel Obregón, Alejandra Wu-Chuang, Jennifer Maye, Jeremie Bornères, Nicolas Versillé, José de la Fuente, Sandra Díaz-Sánchez, Luis G Bermúdez-Humarán, Edgar Torres-Maravilla and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Frontiers in microbiology · 2025
    Article
  12. Review
  13. Microbial community variations in adultFrontiers in microbiology · 2025
    Article
  14. Differential impact ofHeliyon · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Evolution of tick vaccinology.Parasitology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 5 countries.

Lourdes Mateos-HernándezAnses, INRAE, Ecole Nationale Vétérinaire d'Alfort, UMR BIPAR, Laboratoire de Santé Animale, Maisons-Alfort, F-94700, France.
Dasiel ObregónSchool of Environmental Sciences University of Guelph, Guelph, ON, Canada.
Alejandra Wu-ChuangAnses, INRAE, Ecole Nationale Vétérinaire d'Alfort, UMR BIPAR, Laboratoire de Santé Animale, Maisons-Alfort, F-94700, France.
Jennifer MayeSEPPIC Paris La Défense, La Garenne Colombes, 92250, France.
Jeremie BornèresSEPPIC Paris La Défense, La Garenne Colombes, 92250, France.
Nicolas VersilléSEPPIC Paris La Défense, La Garenne Colombes, 92250, France.
José de la FuenteSaBio, Instituto de Investigación en Recursos Cinegéticos (IREC-CSIC-UCLM-JCCM), Ciudad Real, Spain.
Sandra Díaz-SánchezSaBio, Instituto de Investigación en Recursos Cinegéticos (IREC-CSIC-UCLM-JCCM), Ciudad Real, Spain.
Luis G Bermúdez-HumaránUniversité Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350, Jouy-en-Josas, France.
Edgar Torres-MaravillaUniversité Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350, Jouy-en-Josas, France.
Agustín Estrada-PeñaFaculty of Veterinary Medicine, University of Zaragoza, Zaragoza, Spain.
Adnan HodžićInstitute of Parasitology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Ladislav ŠimoAnses, INRAE, Ecole Nationale Vétérinaire d'Alfort, UMR BIPAR, Laboratoire de Santé Animale, Maisons-Alfort, F-94700, France.
Alejandro Cabezas-CruzAnses, INRAE, Ecole Nationale Vétérinaire d'Alfort, UMR BIPAR, Laboratoire de Santé Animale, Maisons-Alfort, F-94700, France.
Air Liquide (France) · FRBipar · FRAgroParisTech · FRÉcole Nationale Vétérinaire d'Alfort · FRInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRInstituto de Investigación en Recursos Cinegéticos · ESMicrobiologie de l’alimentation au service de la santé · FROklahoma State University · USUniversidad de Zaragoza · ESUniversity of Guelph · CAUniversity of Veterinary Medicine Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lack of tools for the precise manipulation of the tick microbiome is currently a major limitation to achieve mechanistic insights into the tick microbiome. Anti-tick microbiota vaccines targeting keystone bacteria of the tick microbiota alter tick feeding, but their impact on the taxonomic and functional profiles of the tick microbiome has not been tested. In this study, we immunized a vertebrate host model (

Indexed as

BacteriaBacterial VaccinesIxodesAnimalsAntibodies, BacterialGastrointestinal MicrobiomeMiceAntibodies, BacterialBacterial Vaccinesanti-microbiota vaccineskeystone bacteriamicrobiome modulationnetworks analysistick

Identifiers

PMID34322135
PMCPMC8312226
OpenAlexW3182443452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.