Evidence map›Paper›PMID 34322116›Full record

ArticleFrontiers in immunology2021

The IL-1 Receptor Is Required to Maintain Neutrophil Viability and Function During

Benjamin Awr Ralph, Melanie Lehoux, Hanna Ostapska, Brendan D Snarr, Alayna K Caffrey-Carr, Richard Fraser, Maya Saleh, Joshua J Obar, Salman T Qureshi, Donald C Sheppard

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  6. Review
  7. Article
  8. Epithelial responses to fungal pathogens.Current opinion in microbiology · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Co-Operative Biofilm Interactions betweenJournal of fungi (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Article
  16. Suppression ofFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Benjamin Awr RalphDepartment of Microbiology and Immunology, McGill University, Montréal, QC, Canada.
Melanie LehouxProgram in Infectious Diseases and Immunology in Global Health, Centre for Translational Biology, The Research Institute of the McGill University Health Center (RI-MUHC), Montréal, QC, Canada.
Hanna OstapskaDepartment of Microbiology and Immunology, McGill University, Montréal, QC, Canada.
Brendan D SnarrDepartment of Microbiology and Immunology, McGill University, Montréal, QC, Canada.
Alayna K Caffrey-CarrDepartment of Microbiology & Immunology, Dartmouth College, Lebanon, NH, United States.
Richard FraserDepartment of Medicine, McGill University, Montréal, QC, Canada.
Maya SalehDepartment of Microbiology and Immunology, McGill University, Montréal, QC, Canada.
Joshua J ObarDepartment of Microbiology & Immunology, Dartmouth College, Lebanon, NH, United States.
Salman T QureshiDepartment of Medicine, McGill University, Montréal, QC, Canada.
Donald C SheppardDepartment of Microbiology and Immunology, McGill University, Montréal, QC, Canada.
McGill University · CAMcGill University Health Centre · CADartmouth College · US

Funding

CIHR 123306CIHR 81361CIHR FDN159902
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsApoptosisAspergillosisAspergillus fumigatusChemokinesGranulocyte Colony-Stimulating FactorHumansInterleukin-1alphaInterleukin-1betaLungMacrophagesMiceMice, Inbred C57BLNeutrophil InfiltrationNeutrophilsPulmonary AspergillosisChemokinesGranulocyte Colony-Stimulating FactorIL1A protein, humanIL1B protein, humanInterleukin-1alphaInterleukin-1betaReceptors, Interleukin-1Aspergillus fumigatuschronic airway infectionG-CSFIL-1neutrophils

Identifiers

PMID34322116
PMCPMC8312098
OpenAlexW3179640952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.