Evidence map›Paper›PMID 34321982›Full record

ArticleComptes rendus. Chimie (Print)2021

Using micro computed tomographic imaging for analyzing kidney stones.

James C Williams, James E Lingeman, Michel Daudon, Dominique Bazin

Open access · diamondAbstract read
In one paragraph

Article in Comptes rendus. Chimie (Print), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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  15. Connexin Mutants Cause Cataracts Through Deposition of Apatite.Frontiers in cell and developmental biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

James C WilliamsDepartment of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, Indiana (USA).
James E LingemanDepartment of Urology, Indiana University School of Medicine, Indianapolis, Indiana (USA).
Michel DaudonUMR S1155, INSERM/UPMC, 4 Rue de la Chine, 75970 Paris Cedex 20, France.
Dominique BazinCNRS, ICP, Bat349, Université Paris-11, 91405 Orsay, France.
Indiana University School of MedicineInserm · FRUniversité Paris-Sud · FR

Funding

STONE FORMATION IN GENETIC HYPERCALCIURIAP01DK056788 · NIDDK · UNIVERSITY OF CHICAGO · PI ASHKAR, TAREK MAURICE · 2000 to 2021
$22.5M
Essential characterization of the Randall's plaque-overgrowth interfaceR01DK124776 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI WILLIAMS, JAMES C · 2020 to 2022
$713k
SkyScan 1176 Micro CT SystemS10OD016208 · OD · INDIANA UNIVERSITY INDIANAPOLIS · PI WILLIAMS, JAMES C · 2014 to 2014
$383k
SkyScan 1172 High-resolution desk-top micro-CT systemS10RR023710 · NCRR · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI WILLIAMS, JAMES C · 2007 to 2007
$297k
NCRR NIH HHS S10 RR023710NIDDK NIH HHS P01 DK056788NIDDK NIH HHS R01 DK124776NIH HHS S10 OD016208
6 · The paper itself

Abstract

Stone analysis is a critical part of the clinical characterization of urolithiasis. This article reviews the strengths and limitations of micro CT in the analysis of stones. Using micro CT alone in a series of 757 stone specimens, micro CT identified the 458 majority calcium oxalate specimens with a sensitivity of 99.6% and specificity of 95.3%. Micro CT alone was also successful in identifying majority apatite, brushite, uric acid, and struvite stones. For some minor minerals-such as apatite in calcium oxalate or calcium salts in uric acid stones-micro CT enables the detection of minute quantities well below 1%. The addition of a standard for calibrating X-ray attenuation values improves the ability of micro CT to identify common stone minerals. The three-dimensional nature of micro CT also allows for the visualization of surface features in stones, which is valuable for the study of stone formation.

Indexed as

apatitebrushitecalcium oxalatemicro CTstone analysisstruviteuric acidurolithiasis

Identifiers

PMID34321982
PMCPMC8312732
OpenAlexW3176035717

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.