Evidence map›Paper›PMID 34321956›Full record

ArticleJournal of carcinogenesis2021

Demographic and clinicopathological Profile of Gall Bladder Cancer Patients: Study from a tertiary care center of the Sub-Himalayan region in Indo-Gangetic Belt.

Amit Gupta, Sweety Gupta, Rohik Anjum T Siddeek, Jaine John Chennatt, Tanuj Singla, Deepak Rajput, Navin Kumar, Amit Sehrawat, Sanjeev Kishore, Manoj Gupta

Open access · goldAbstract read
In one paragraph

Article in Journal of carcinogenesis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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  4. A prospective pilot study to evaluate the impact of palliative radiotherapy in upfront inoperable/chemo unfit patients with extrahepatic biliary tract tumors.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Amit GuptaDepartment of Surgery, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Sweety GuptaDepartment of Radiation Oncology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Rohik Anjum T SiddeekDepartment of Surgery, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Jaine John ChennattDepartment of Surgery, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Tanuj SinglaDepartment of Surgery, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Deepak RajputDepartment of Surgery, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Navin KumarDepartment of Surgery, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Amit SehrawatDepartment of Medical Oncology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Sanjeev KishoreDepartment of Pathology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Manoj GuptaDepartment of Radiation Oncology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
All India Institute of Medical Sciences Rishikesh · INRadiation Oncology Associates · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGall bladder cancer (GBC) accounts for 80%-95% of biliary tract malignancies in the world. There is however striking variability in the global incidence of gallbladder cancer, reaching epidemic levels for some regions and ethnicities. The aim of this study was to evaluate the demographic and clinicopathological profile of the gallbladder cancer patients. MATERIALS AND

methodsAll patients of carcinoma gall bladder presenting to department of surgery in hepatopancreaticobiliary unit from July 2017 to November 2020 were included in this study. A proforma containing all the relevant details including history, examination, blood, radiology, and pathological investigations was filled.

resultsA total of 326 patients of GBC were analyzed. The majority (75%) were found to be females with a mean age of 55 years. Pain abdomen was the most common presenting symptom in 81% of patients. The most common stage of presentation was stage IV and only 6 were in stage I. Two hundred and thirty three (71.4%) patients had metastatic disease at presentation. Liver infiltration at the time of diagnosis was present in 89% of patients. The most common site of metastasis was found in the liver (23.3%). GBC was more common in patients with A blood group. Baseline serum albumin levels were found to be significantly associated with the staging of GBC.

conclusionsDue to the non specific symptoms patients of GBC present at very advanced stages, high index of suspicion and health education seems to play an important role in early detection and improvement of survival.

Indexed as

Cholelithiasisgallbladder cancerincidencemetastasis

Identifiers

PMID34321956
PMCPMC8312375
OpenAlexW3167086243

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.