Evidence map›Paper›PMID 34321900›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2021

Blood Glucose and Renal Function Evaluation in Patients with Viral Hepatitis.

Wen-Tung Hsu, Deng-Ho Yang, Chun-Cheng Liao, Jia-Wen Chen, Wen-Hsiu Hsu, Chia-Wen Kuo, Hung-Chang Hsu, Sheng-Huang Chang, Li-Mien Chen

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Wen-Tung HsuDivision of Laboratory, Taichung Armed Force General Hospital, Taichung, Taiwan, Republic of China.
Deng-Ho YangDivision of Laboratory, Taichung Armed Force General Hospital, Taichung, Taiwan, Republic of China.
Chun-Cheng LiaoSchool of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China.ORCID 0000-0002-7508-6297
Jia-Wen ChenMedicine Laboratory, Ministry of Health and Welfare Feng Yuan Hospital, Taichung, Taiwan, Republic of China.
Wen-Hsiu HsuSchool of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China.
Chia-Wen KuoSchool of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China.
Hung-Chang HsuDivision of Laboratory, Ching Chyuan Hospital, Taichung, Taiwan, Republic of China.ORCID 0000-0001-9401-1699
Sheng-Huang ChangTsaotun Psychiatric Center, Ministry of Health and Welfare, Nantou, Taiwan, Republic of China.
Li-Mien ChenDepartment of Internal Medicine, Taichung Armed Force General Hospital, Taichung, Taiwan, Republic of China.
Taichung Armed Forces General Hospital · TWMinistry of Health and Welfare · TWCheng Ching Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the blood glucose and renal function, determine the prevalence of hyperglycemia/diabetes mellitus (DM) and renal disease (nephropathy), and investigate the association between hyperglycemia/DM and renal disease in patients with viral hepatitis (VH). PATIENTS AND

methodsA total of 491 subjects were included in the study. Patients with VH were further divided into the hepatitis B virus (HBV) infection, hepatitis C virus (HCV) infection, and HBV-HCV co-infection subgroups. Fasting blood glucose, glycated hemoglobin (HbA1c), glycated albumin (GA), glutamic oxaloacetic transaminase (GOT), creatinine (Cr), and cystatin C (Cys C) levels were measured. Urine microalbumin levels were also assessed. Formulas for estimated average glucose calculated using glycated albumin(eAG(GA)), estimated average glucose calculated using HbA1c (eAG(HbA1c)), and estimated glomerular filtration rate calculated using cystatin C (eGFRcys) were used to evaluate the average glucose and renal function.

resultsThe prevalence of hyperglycemia/DM and renal disease was significantly higher in the VH group, especially in the HCV subgroup. The prevalence of renal disease was significantly higher in patients with VH with eAG(GA) ≥200 mg/dL.

conclusionOur study used multiple parameters to evaluate blood glucose and renal function in patients with VH and found that hyperglycemia/DM and renal disease are closely associated with VH, especially in subjects with HCV infection. Patients with VH, especially those with HCV infection and hyperglycemia/DM, were particularly vulnerable to renal disease.

Indexed as

diabetes mellitushyperglycemianephropathyrenal diseaseviral hepatitis

Identifiers

PMID34321900
PMCPMC8312512
OpenAlexW3184369966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.