Evidence map›Paper›PMID 34321868›Full record

ArticleDrug design, development and therapy2021

A Network Pharmacology-Based Investigation to the Pharmacodynamic Material Basis and Mechanisms of the Anti-Inflammatory and Anti-Viral Effect of

Jiuling Deng, Ying Ma, Yuqiong He, Hong Yang, Yanhong Chen, Liang Wang, Doudou Huang, Shi Qiu, Xia Tao, Wansheng Chen

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 43 citations in OpenAlex.

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  7. Application of network pharmacology in synergistic action of Chinese herbal compounds.Theory in biosciences = Theorie in den Biowissenschaften · 2024
    Review
  8. Antibiotics (Basel, Switzerland) · 2024
    Article
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  11. Review
  12. Extract ofAntioxidants (Basel, Switzerland) · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Anti-Inflammatory Effects of Phytochemical Components ofMolecules (Basel, Switzerland) · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jiuling Deng *Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Ying Ma *Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, People's Republic of China.
Yuqiong He *Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Hong YangDepartment of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, People's Republic of China.ORCID 0000-0003-1250-5156
Yanhong ChenDepartment of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, People's Republic of China.
Liang WangInstitute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Doudou HuangInstitute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Shi Qiu *Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Xia TaoDepartment of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, People's Republic of China.
Wansheng ChenInstitute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Shanghai University of Traditional Chinese Medicine · CNSecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose

methodsUltra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF-MS) was adopted for the chemical profiling of

resultsSeventy-three compounds have been identified from

conclusionAs the pharmacodynamics material basis of

Indexed as

Network PharmacologyAnimalsAnti-Inflammatory AgentsAntiviral AgentsIsatisMiceRAW 264.7 CellsSignal TransductionAnti-Inflammatory AgentsAntiviral Agentsbioassay analysisIsatis indigoticanetwork analysisUPLC-Q-TOF-MS

Identifiers

PMID34321868
PMCPMC8312626
OpenAlexW3191942291

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.