Evidence map›Paper›PMID 34321848›Full record

ReviewWorld journal of gastroenterology2021

Gut microbiota in obesity.

Bing-Nan Liu, Xiao-Tong Liu, Zi-Han Liang, Ji-Hui Wang

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06901739 (New Dietary Intervention Strategies on the Intestinal Microbiota to Improve Mental Health Subjects With Obesity), which is not on this map. Cited by 319 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
319citing papers in PubMed, 11 pooled it
27.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06901739 narecruitingnot on this mapstarted 2025, after this paper: background citation

New Dietary Intervention Strategies on the Intestinal Microbiota to Improve Mental Health Subjects With Obesity: Therapeutic Potential of a Synbiotic.

TypeinterventionalSponsorCelia BañulsRan2025 to 2027Enrolled120ConditionsObese Patients (BMI ≥ 30 kg/m²), Anxiety, Depressive DisorderArmsSynbiotic, Placebo
3 · Its place in the literature

Who cites it

319 citing papers in PubMed, 11 syntheses or guidelines pooled it, 565 citations in OpenAlex.

  1. Pooled it
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  3. Biopsychosocial and Environmental Factors That Impact Brain-Gut-Microbiome Interactions in Obesity.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Pooled it
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  5. Impact of bariatric surgery on gut microbiota in obese patients: A systematic review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Pooled it
  6. Pooled it
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  11. Nutrients · 2024
    Pooled it
  12. Trial
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  18. Review
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259 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bing-Nan LiuSchool of Bioengineering, Dalian Polytechnic University, Dalian 116034, Liaoning Province, China.
Xiao-Tong LiuSchool of Bioengineering, Dalian Polytechnic University, Dalian 116034, Liaoning Province, China.
Zi-Han LiangSchool of Bioengineering, Dalian Polytechnic University, Dalian 116034, Liaoning Province, China.
Ji-Hui WangSchool of Bioengineering, Dalian Polytechnic University, Dalian 116034, Liaoning Province, China.
Dalian Polytechnic University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is a major global health problem determined by heredity and environment, and its incidence is increasing yearly. In recent years, increasing evidence linking obesity to the gut microbiota has been reported. Gut microbiota management has become a new method of obesity treatment. However, the complex interactions among genetics, environment, the gut microbiota, and obesity remain poorly understood. In this review, we summarize the characteristics of the gut microbiota in obesity, the mechanism of obesity induced by the gut microbiota, and the influence of genetic and environmental factors on the gut microbiota and obesity to provide support for understanding the complex relationship between obesity and microbiota. At the same time, the prospect of obesity research related to the gut microbiota is proposed.

Indexed as

Gastrointestinal MicrobiomeDysbiosisHumansObesityDysbiosisEcologyGeneticsGut microbiotaObesity

Identifiers

PMID34321848
PMCPMC8291023
OpenAlexW3186747227

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.