Evidence map›Paper›PMID 34321817›Full record

ArticleMiddle East African journal of ophthalmology

Safety and Efficacy of Epithelial Island Crosslinking in Keratoconus with Thinnest Pachymetry less than 400µ.

Hisham A Omar, Mohamed-Sameh H El-Agha, Mohamed A Hassaballah, Noha M Khalil

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Middle East African journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hisham A OmarDepartment of Ophthalmology, Kasr Al Ainy School of Medicine, Cairo University, Giza, Egypt.
Mohamed-Sameh H El-AghaDepartment of Ophthalmology, Kasr Al Ainy School of Medicine, Cairo University, Giza, Egypt.
Mohamed A HassaballahDepartment of Ophthalmology, Kasr Al Ainy School of Medicine, Cairo University, Giza, Egypt.
Noha M KhalilDepartment of Ophthalmology, Kasr Al Ainy School of Medicine, Cairo University, Giza, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the efficacy and safety of epithelial-island crosslinking (EI-CXL) in keratoconus with corneas thinner than 400 µm.

methodsTwenty-six patients (30 eyes) underwent EI-CXL (preserving the epithelium over the thinnest area), using standard protocol (3 mW/cm

resultsAfter 1 year, mean UCDVA improved from 1.29 preoperatively to 1.17 (

conclusionEI-CXL halted keratoconus progression over a 1-year period. This was associated with statistically significant endothelial loss, but less than seen with conventional epi-off CXL in thinner corneas.

Indexed as

KeratoconusPhotochemotherapyCollagenCorneal PachymetryCross-Linking ReagentsFollow-Up StudiesHumansPhotosensitizing AgentsRiboflavinUltraviolet RaysVisual AcuityCollagenCross-Linking ReagentsPhotosensitizing AgentsRiboflavinCustomized epithelial debridementdemarcation lineepithelial island crosslinkingkeratoconuspachymetry

Identifiers

PMID34321817
PMCPMC8270024
OpenAlexW3159696470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.