Evidence map›Paper›PMID 34321774›Full record

ArticleJournal of cytology

Prognostic Role of Intragastric Cytopathology and Microbiota in Surgical Patients with Stomach Cancer.

Edoardo Virgilio, Enrico Giarnieri, Elisabetta Carico, Monica Montagnini, Sandra Villani, Michele Fiorenti, Marco Cavallini, Filippo Montali, Renato Costi

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cytology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Edoardo VirgilioDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Enrico GiarnieriDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University "Sapienza", St. Andrea Hospital, Rome, Italy.
Elisabetta CaricoDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University "Sapienza", St. Andrea Hospital, Rome, Italy.
Monica MontagniniDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University "Sapienza", St. Andrea Hospital, Rome, Italy.
Sandra VillaniDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University "Sapienza", St. Andrea Hospital, Rome, Italy.
Michele FiorentiDepartment of Anesthesiology and Reanimation, St. Andrea Hospital, Rome, Italy.
Marco CavalliniDepartment of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University "Sapienza," Rome, Italy.
Filippo MontaliDepartment of General Surgery, di Vaio Hospital, Fidenza (PR), Italy.
Renato CostiDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
University of Parma · ITCTO Andrea Alesini · ITUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the last decade, analysis of malignant cells and flora in gastric lavage (GL) has provided interesting data on pathogenesis of gastric cancer (GC). For this study, combining such two aspects into one cyto-microbiologic category, we tested the prognostic role of the presence/absence of cancer cells (GL1/GL0) and bacterial microbiota (MB1/MB0) in our GC population. MATERIAL AND

methodsBetween April 2012 and August 2019, 79 surgical patients with GC were prospectively investigated with the determination of GL MB.

resultsCompared with GL1 MB0, GL1 MB1 strongly correlated with advanced GC, portended poorer overall survival (OS) (45.8 months

conclusionIn the light of our results, the cyto-microbiologic parameter of GL MB should be used to gain a better prognosis of GC patients. Administration of antimicrobial treatment for MB1 subjects should be entertained because it could reduce the risk of oncogenesis.

Indexed as

Fluid cytologygastric cancergastric microbiotagastrointestinal cytologynon-gynecologic cytopathology

Identifiers

PMID34321774
PMCPMC8280856
OpenAlexW3160627311

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.