Evidence map›Paper›PMID 34321564›Full record

ArticleScientific reports2021

Evaluation of retinal vascular density and related factors in youth myopia without maculopathy using OCTA.

Tiantian Wang, Hui Li, Rongrong Zhang, Yan Yu, Xin Xiao, Changfan Wu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tiantian Wang *Department of Ophthalmology, Maanshan Shiqiye Hospital at Maanshan, Maanshan, 243000, Anhui, China.
Hui Li *Department of Ophthalmology, Yijishan Hospital of Wannan Medical College at Wuhu, 92 West Zheshan Rd, Wuhu, 241000, Anhui, People's Republic of China.
Rongrong ZhangDepartment of Ophthalmology, Yijishan Hospital of Wannan Medical College at Wuhu, 92 West Zheshan Rd, Wuhu, 241000, Anhui, People's Republic of China.
Yan YuDepartment of Ophthalmology, Yijishan Hospital of Wannan Medical College at Wuhu, 92 West Zheshan Rd, Wuhu, 241000, Anhui, People's Republic of China.
Xin XiaoVisual Science and Optometry Center of Guangxi, People's Hospital of Guangxi Zhuang Autonomous Region at Nanning, Nanning, 530000, Guangxi, China.
Changfan WuDepartment of Ophthalmology, Yijishan Hospital of Wannan Medical College at Wuhu, 92 West Zheshan Rd, Wuhu, 241000, Anhui, People's Republic of China. wucangfan@sina.com.
First Affiliated Hospital of Wannan Medical College · CNThe People's Hospital of Guangxi Zhuang Autonomous Region · CNWuhu No 1 People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the retinal vascular flow density changes of myopic eyes of young adults using optical coherence tomography angiography and the factors affecting these changes. In this cross-sectional study, 90 eyes of 45 participants were analyzed and divided into three groups: mild, moderate, and high myopia (without pathological changes). Macular and radial peripapillary capillary flow densities were measured using optical coherence tomography angiography. Their relationships with the axial length, the spherical equivalent of the refractive error, and age were analyzed using analysis of variance, Pearson's correlation coefficient, and multivariate linear regression analysis. Superficial and deep macular vascular densities were significantly decreased in the high myopia group compared to the other groups. In the high myopia group, the nasal peripapillary flow density decreased, whereas the flow density inside the disc increased. The axial length negatively correlated with the superficial and deep macular vascular density, but positively correlated with the vascular density inside the disc. The spherical equivalent of the refractive error negatively correlated with the macular vascular density. The retinal vascular density decreased in the high myopia group. Hence, the microvascular network inside the disc may have a compensatory action in the hypoxic setting of high myopia.

Indexed as

AdultAgedAged, 80 and overFemaleFluorescein AngiographyHumansMacula LuteaMacular DegenerationMaleMicrovascular DensityMicrovesselsMiddle AgedMyopiaRefraction, OcularRetinaRetinal Diseases

Identifiers

PMID34321564
PMCPMC8319333
OpenAlexW3186994071

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.