ArticleScientific reports2021
High triglyceride-glucose index is associated with early recurrent ischemic lesion in acute ischemic stroke.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- The impact of triglyceride-glucose index on ischemic stroke: a systematic review and meta-analysis.Cardiovascular diabetology · 2023Pooled it
- Triglyceride-Glucose Index and Ischemic Stroke Burden in Permanent Versus Paroxysmal Atrial Fibrillation: A Real-World Retrospective Cohort Study.Metabolites · 2026Article
- The Association Between Cholesterol, High-Density Lipoprotein, and Glucose Index and Mortality in Young and Middle-Aged Adults With Diabetes or Prediabetes: NHANES Data (1999-2018).Cardiology research · 2026Article
- Association of the hsCRP- triglyceride-glucose index (CTI) with early infarct growth rate in acute ischemic stroke due to large artery occlusion.Frontiers in aging neuroscience · 2026Article
- Association of higher triglyceride glucose index and triglyceride to high density lipoprotein cholesterol ratio with early-onset post-stroke depression.Scientific reports · 2025Article
- Can the triglyceride-glucose index predict stroke outcomes? A systematic review and meta-analysis.Pakistan journal of medical sciences · 2025Review
- Effect of atherogenic index of plasma and triglyceride-glucose index on early neurological deterioration of patients with large artery atherosclerotic ischemic stroke.Diabetology & metabolic syndrome · 2025Article
- Associations of triglyceride glucose-body mass index with short-term mortality in critically ill patients with ischemic stroke.Cardiovascular diabetology · 2025Article
- Correlation of triglyceride glucose index with all cause mortality in acute myocardial infarction patients following percutaneous coronary intervention.Scientific reports · 2025Article
- The relationship between remote diffusion-weighted imaging lesions and the triglyceride-glucose index and clinical outcomes in patients with intracerebral hemorrhage.Frontiers in neurology · 2025Article
- TyG × waist circumference composite indicator and cardiovascular disease risk in older adults across multiple regions: a cross-sectional study.Frontiers in endocrinology · 2025Article
- Nomogram Models Integrating TyG Index for Predicting Early Neurological Deterioration and 90-Day Outcomes in AIS Patients Undergoing IVT.Journal of central nervous system disease · 2025Article
- Development and validation of an AMR-based predictive model for post-PCI upper gastrointestinal bleeding in NSTEMI patients.Frontiers in endocrinology · 2025Article
- Analyzing the correlation between acute ischemic stroke and triglyceride-glucose index based on ordered logistic regression.Frontiers in neurology · 2025Article
- Triglyceride-glucose index as a biomarker to differentiate stroke etiologic subtypes: a hospital-based cross-sectional study.Biomarkers in medicine · 2025Article
- Association of the Triglyceride Glucose Index With Outcomes in Acute Ischemic Stroke Injury.Cureus · 2024Article
- Association of weight-adjusted-waist index with all-cause and cardiovascular mortality in individuals with diabetes or prediabetes: a cohort study from NHANES 2005-2018.Scientific reports · 2024Article
- Non-linear association of triglyceride-glucose index with cardiovascular and all-cause mortality in T2DM patients with diabetic kidney disease: NHANES 2001-2018 retrospective cohort study.Lipids in health and disease · 2024Article
- Triglyceride-Related Parameters and Symptomatic Atherosclerotic Lesions in Patients With Ischemic Stroke.Journal of lipid and atherosclerosis · 2024Article
- Association of higher triglyceride-glucose index and triglyceride-to-high-density lipoprotein cholesterol ratio with early neurological deterioration after thrombolysis in acute ischemic stroke patients.Frontiers in neurology · 2024Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The triglyceride-glucose (TyG) index has been associated with various metabolic, cardiovascular, and cerebrovascular diseases. We evaluated the association between the TyG index and early recurrent ischemic lesions (ERILs) in patients with acute ischemic stroke (AIS). We included consecutive patients diagnosed with AIS between 2010 and 2016. ERILs were defined as new diffusion-weighted imaging lesions outside the initial symptomatic lesion area. The TyG index was calculated using the following formula: log scale of fasting triglyceride × fasting glucose/2. A total of 176 patients with AIS were evaluated. In the multivariable analysis, the TyG index remained significant (adjusted odds ratio [aOR] 2.63, 95% confidence interval [CI] 1.34-5.15). This close correlation between the TyG index and ERIL was pronounced in ERIL-same group (aOR 2.84, 95% CI 1.40-5.78), but not in ERIL-different group. When comparing the relationship between the TyG index and ERIL by stroke mechanisms, only the intracranial- and extracranial-large artery atherosclerosis groups showed significantly higher TyG index values in patients with ERIL than those without. In conclusion, a higher TyG index was associated with ERIL, especially ERIL-same, in patients with AIS. The TyG index appears to be involved in ERIL occurrence by a mechanism related to atherosclerosis.
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