Evidence map›Paper›PMID 34321515›Full record

Observational studyScientific reports2021

Trends in type 2 diabetes mellitus disease burden in European Union countries between 1990 and 2019.

Richard Goodall, Andrew Alazawi, Will Hughes, Vassiliki Bravis, Justin D Salciccioli, Dominic C Marshall, Conor Crowley, Joseph Shalhoub

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 88 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Richard Goodall *Imperial College London, London, UK. r.goodall@imperial.ac.uk.ORCID 0000-0002-6990-7087
Andrew Alazawi *Medical Data Research Collaborative, London, UK.ORCID 0000-0001-6564-5828
Will HughesMedical Data Research Collaborative, London, UK.ORCID 0000-0003-0849-671X
Vassiliki BravisImperial College Healthcare NHS Trust, Imperial College London, London, UK.ORCID 0000-0003-4493-1993
Justin D SalciccioliMedical Data Research Collaborative, London, UK.ORCID 0000-0001-8092-0883
Dominic C MarshallMedical Data Research Collaborative, London, UK.
Conor CrowleyMedical Data Research Collaborative, London, UK.ORCID 0000-0002-0728-4785
Joseph ShalhoubMedical Data Research Collaborative, London, UK.ORCID 0000-0003-1011-7440
Imperial College Healthcare NHS Trust · GBBrigham and Women's Hospital · USCambridge University Hospitals NHS Foundation Trust · GBHealth Data Research UK · GBLahey Medical Center · USQueen Mary University of London · GB

Funding

Department of Health
6 · The paper itself

Abstract

This observational study aimed to assess trends in type 2 diabetes mellitus (T2DM) disease burden in European Union countries for the years 1990-2019. Sex specific T2DM age-standardised prevalence (ASPRs), mortality (ASMRs) and disability-adjusted life-year rates (DALYs) per 100,000 population were extracted from the Global Burden of Disease (GBD) Study online results tool for each EU country (inclusive of the United Kingdom), for the years 1990-2019. Trends were analysed using Joinpoint regression analysis. Between 1990 and 2019, increases in T2DM ASPRs were observed for all EU countries. The highest relative increases in ASPRs were observed in Luxembourg (males + 269.1%, females + 219.2%), Ireland (males + 191.9%, females + 165.7%) and the UK (males + 128.6%, females + 114.6%). Mortality trends were less uniform across EU countries, however a general trend towards reducing T2DM mortality was observed, with ASMRs decreasing over the 30-year period studied in 16/28 countries for males and in 24/28 countries for females. The UK observed the highest relative decrease in ASMRs for males (- 46.9%). For females, the largest relative decrease in ASMRs was in Cyprus (- 67.6%). DALYs increased in 25/28 countries for males and in 17/28 countries for females between 1990 and 2019. DALYs were higher in males than females in all EU countries in 2019. T2DM prevalence rates have increased across EU countries over the last 30 years. Mortality from T2DM has generally decreased in EU countries, however trends were more variable than those observed for prevalence. Primary prevention strategies should continue to be a focus for preventing T2DM in at risk groups in EU countries.

Indexed as

Global Burden of DiseaseAgedCost of IllnessDiabetes Mellitus, Type 2European UnionFemaleHumansIrelandLuxembourgMaleMiddle AgedPersons with DisabilitiesQuality-Adjusted Life YearsRisk FactorsUnited Kingdom

Identifiers

PMID34321515
PMCPMC8319179
OpenAlexW3183901369

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.