Evidence map›Paper›PMID 34321511›Full record

ArticleScientific reports2021

Long noncoding RNA CCAT1 rs67085638 SNP contribution to the progression of gastric cancer in a Polish population.

Tomasz Olesiński, Anna Lutkowska, Adam Balcerek, Anna Sowińska, P Piotrowski, Tomasz Trzeciak, Tomasz Maj, Piotr Hevelke, Pawel P Jagodziński

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Tomasz OlesińskiDepartment of Oncological Gastroenterology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Anna LutkowskaDepartment of Biochemistry and Molecular Biology, Poznań University of Medical Sciences, 6 Święcickiego St., 60-781, Poznan, Poland.
Adam BalcerekDepartment of Biochemistry and Molecular Biology, Poznań University of Medical Sciences, 6 Święcickiego St., 60-781, Poznan, Poland.
Anna SowińskaDepartment of Computer Science and Statistics, Poznań University of Medical Sciences, Poznan, Poland.
P PiotrowskiMolecular Biology Department, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
Tomasz TrzeciakDepartment of Orthopedics and Traumatology, Poznan University of Medical Sciences, Poznan, Poland.
Tomasz MajDepartment of Oncological Gastroenterology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Piotr HevelkeDepartment of Oncological Gastroenterology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Pawel P JagodzińskiDepartment of Biochemistry and Molecular Biology, Poznań University of Medical Sciences, 6 Święcickiego St., 60-781, Poznan, Poland. pjagodzi@ump.edu.pl.
Poznan University of Medical Sciences · PLThe Maria Sklodowska-Curie National Research Institute of Oncology · PLHeliodor Swiecicki Clinical Hospital · PLNational Institute of Geriatrics, Rheumatology and Rehabilitation · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of the long noncoding RNA CCAT1 NC_000008.10:g.128220661C > T (rs67085638) in the development of colon cancer has been reported. Therefore, we assessed the prevalence of rs67085638 in patients with gastric cancer (GC). We also evaluated the effect of rs67085638 on B-cell-specific Moloney leukaemia virus insertion site 1 (BMI1) transcripts in primary GC and counterpart histopathologically confirmed disease-free margin tissue. Using high-resolution melting analysis, we evaluated rs67085638 frequency in patients with the GC genotype (n = 214) and controls (n = 502) in a Polish Caucasian population. qRT-PCR was used to determine BMI1 transcripts. We observed the trend of rs67085638 association in all patients with GC (p

Indexed as

Genetic Predisposition to DiseaseAdultCell ProliferationDisease ProgressionFemaleGene Expression Regulation, NeoplasticGenotypeHumansLymphatic MetastasisMaleMiddle AgedPolycomb Repressive Complex 1Polymorphism, Single NucleotideRNA, Long NoncodingStomach NeoplasmsBMI1 protein, humanCCAT1 long noncoding RNA, humanPolycomb Repressive Complex 1RNA, Long Noncoding

Identifiers

PMID34321511
PMCPMC8319342
OpenAlexW3186199695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.