Evidence map›Paper›PMID 34321460›Full record

ArticleTranslational psychiatry2021

Genome wide analysis implicates upregulation of proteasome pathway in major depressive disorder.

Shaked Belaish, Ifat Israel-Elgali, Guy Shapira, Israel Krieger, Aviv Segev, Uri Nitzan, Michael Majer, Yuval Bloch, Abraham Weizman, David Gurwitz and 2 more

Abstract read
In one paragraph

Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shaked BelaishSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0001-6154-8211
Ifat Israel-ElgaliSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Guy ShapiraSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0001-9376-4955
Israel KriegerSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Aviv SegevSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Uri NitzanSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Michael MajerDepartment of Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel.
Yuval BlochSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Abraham WeizmanSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0002-9765-8938
David GurwitzSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0002-9363-1869
Noam ShomronSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. nshomron@post.tau.ac.il.ORCID 0000-0001-9913-6124
Libi HertzbergSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. libi.hertzberg@gmail.com.ORCID 0000-0002-7895-8089

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Major Depressive DisorderGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansPolymorphism, Single NucleotideProteasome Endopeptidase ComplexUp-RegulationProteasome Endopeptidase Complex

Identifiers

PMID34321460
PMCPMC8319154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.