Evidence map›Paper›PMID 34321338›Full record

Trial reportPediatrics2021

Patient Portal Reminders for Pediatric Influenza Vaccinations: A Randomized Clinical Trial.

Carlos Lerner, Christina Albertin, Alejandra Casillas, O Kenrik Duru, Michael K Ong, Sitaram Vangala, Sharon Humiston, Sharon Evans, Michael Sloyan, Craig R Fox and 3 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06657573 (AI-enabled Vaccine Chatbot for Improving Influenza Vaccination Uptake in Children), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06657573 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

AI-enabled Vaccine Chatbot for Improving Influenza Vaccination Uptake in Children: a Cluster Randomized Trial

TypeinterventionalSponsorFudan UniversityRan2024 to 2025Enrolled1,200ConditionsInfluenza VaccinesArmsAn AI-enabled chatbot tailored for influenza vaccine consultation
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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  8. Review
  9. Embedding research study recruitment within the patient portal preCheck-in.Journal of the American Medical Informatics Association : JAMIA · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Carlos LernerDepartment of Pediatrics and Mattel Children's Hospital clerner@mednet.ucla.edu.
Christina AlbertinDepartment of Pediatrics and Mattel Children's Hospital.
Alejandra CasillasDepartment of Medicine, David Geffen School of Medicine.
O Kenrik DuruDepartment of Medicine, David Geffen School of Medicine.
Michael K OngDepartment of Medicine, David Geffen School of Medicine.
Sitaram VangalaDepartment of Medicine, David Geffen School of Medicine.
Sharon HumistonDepartment of Pediatrics, Children's Mercy, Kansas City, Missouri.
Sharon EvansInformation Services and Solutions, University of California, Los Angeles, Health, Los Angeles, California.
Michael SloyanInformation Services and Solutions, University of California, Los Angeles, Health, Los Angeles, California.
Craig R FoxDepartment of Medicine, David Geffen School of Medicine.
Jonathan E BogardAnderson School of Management.
Sarah FriedmanDepartment of Pediatrics and Mattel Children's Hospital.
Peter G SzilagyiDepartment of Pediatrics and Mattel Children's Hospital.

Funding

Improving Influenza Vaccination Delivery Across a Health System by the Electronic Health Records Patient PortalR01AI135029 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SZILAGYI, PETER G · 2018 to 2022
$3.7M
NIAID NIH HHS R01 AI135029
6 · The paper itself

Abstract

objectivesIn a large health system, we evaluated the effectiveness of electronic health record patient portal reminders in increasing pediatric influenza vaccination rates.

methodsWe conducted an intention-to-treat randomized clinical trial of 22 046 children from 6 months to <18 years of age in 53 primary care practices. Patients (or parent and/or proxies) who were active portal users were randomly assigned to receive reminder messages framed as gains or losses or no messages. They were separately randomly assigned to receive a precommitment message before the influenza season. The primary outcome was receipt of ≥1 seasonal influenza vaccinations. Additionally, children 6 months to <3 years of age due for a second influenza vaccine were randomly assigned to receive a reminder or no reminder for the second vaccination.

resultsFirst-dose influenza vaccination rates were 56.9% in the control group, 58.0% in the loss-frame reminders group (

conclusionsPatient portal reminders for influenza vaccines in children, whether framed as gains or losses, did not increase first-dose influenza vaccination rates but were highly effective for the second dose of the vaccine.

Indexed as

Influenza VaccinesPatient PortalsReminder SystemsAdolescentChildChild, PreschoolFemaleHumansInfantInfluenza, HumanIntention to Treat AnalysisMaleSingle-Blind MethodInfluenza Vaccines

Identifiers

PMID34321338
PMCPMC8669575

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.