Evidence map›Paper›PMID 34321232›Full record

SynthesisBMJ global health2021

Characteristics and effects of integrated nutrition and stimulation interventions to improve the nutritional status and development of children under 5 years of age: a systematic review and meta-analysis.

Sophiya Dulal, Audrey Prost, Surendra Karki, Naomi Saville, Dafna Merom

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ global health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07004608 (The Effectiveness Of A Community-based Video-facilitated Parenting Intervention For Child Development Integrated Into Routine Maternal And Child Care Services In India), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07004608 completednot on this mapstarted 2023, after this paper: background citation

The Effectiveness Of A Community-based Video-facilitated Parenting Intervention For Child Development Integrated Into Routine Maternal And Child Care Services In India: Study Protocol

TypeobservationalSponsorSangathRan2023 to 2024Enrolled1,824ConditionsChild Development, Child Nutrition and Early Child DevelopmentArmsAalana Palana
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 49 citations in OpenAlex.

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  15. Commentary: A nurturing care perspective on bundling interventions - a reflection on Jeong et al. (2023).Journal of child psychology and psychiatry, and allied disciplines · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Sophiya DulalSchool of Health Sciences, Western Sydney University, Penrith South, New South Wales, Australia dulal.sophiya@gmail.com.ORCID 0000-0002-2244-613X
Audrey ProstInstitute for Global Health, University College London, London, UK.
Surendra KarkiSchool of Population Health, University of New South Wales, Sydney, New South Wales, Australia.
Naomi SavilleInstitute for Global Health, University College London, London, UK.
Dafna MeromSchool of Health Sciences, Western Sydney University, Penrith South, New South Wales, Australia.
University College London · GBWestern Sydney University · AUAustralian Red Cross Lifeblood · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAround 250 million children in low-income and middle-income countries are at risk of not fulfilling their developmental potential. There is a need to update syntheses investigating the effects of combined nutrition and stimulation interventions on children's growth and development and identify intervention characteristics associated with positive effects.

methodsWe did a systematic review to: (1) understand the effects of integrated nutrition and stimulation interventions versus (i) usual care and (ii) standalone nutrition or stimulation interventions, on the growth and development of children under five; (2) explore intervention characteristics (delivery strategies, behaviour change techniques, intensity and personnel) associated with positive effects. We searched eight databases for studies published from inception to 16 November 2020. Eligible studies were randomised and non-randomised controlled trials of integrated nutrition and stimulation interventions examining growth and developmental outcomes. We performed meta-analyses for length-for-age/height-for-age, weight-for-age and weight-for-length/weight-for-height Z scores and cognitive, motor and language development scores, and subgroup analyses by intervention characteristics. We conducted random-effects metaregression to assess potential subgroup differences in outcomes by intervention characteristics.

resultsTwenty trials were included in the meta-analysis. Pooled effect sizes showed significant benefits of integrated interventions on developmental outcomes compared with usual care and standalone nutrition interventions (

conclusionIntegrated interventions have greater benefits for children's development than usual care or standalone nutrition interventions, especially in settings with high levels of undernutrition. Future studies should use standardised reporting of implementation processes to identify intervention characteristics linked to positive effects.

Indexed as

Nutritional StatusChildChild, PreschoolHumanschild healthnutritionpublic healthsystematic review

Identifiers

PMID34321232
PMCPMC8319976
OpenAlexW3184536856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.