Evidence map›Paper›PMID 34320997›Full record

ArticleJournal of nanobiotechnology2021

Intratumoral administration of astatine-211-labeled gold nanoparticle for alpha therapy.

Hiroki Kato, Xuhao Huang, Yuichiro Kadonaga, Daisuke Katayama, Kazuhiro Ooe, Atsushi Shimoyama, Kazuya Kabayama, Atsushi Toyoshima, Atsushi Shinohara, Jun Hatazawa and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Ultrasmall AuExploration (Beijing, China) · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Small science · 2025
    Review
  11. Review
  12. Article
  13. Development of aJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  14. Article
  15. Review
  16. Recent advances in the development ofAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Review
  17. Molecules (Basel, Switzerland) · 2024
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Hiroki KatoDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. kato-h@umin.org.ORCID http://orcid.org/0000-0003-0838-6772
Xuhao HuangDepartment of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka, 560-0043, Japan.
Yuichiro KadonagaDivision of Science, Institute for Radiation Sciences, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka, 560-0043, Japan.
Daisuke KatayamaDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Kazuhiro OoeDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Atsushi ShimoyamaDepartment of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka, 560-0043, Japan.
Kazuya KabayamaDepartment of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka, 560-0043, Japan.
Atsushi ToyoshimaDivision of Science, Institute for Radiation Sciences, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka, 560-0043, Japan.
Atsushi ShinoharaDepartment of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka, 560-0043, Japan.
Jun HatazawaResearch Center for Nuclear Physics, Osaka University, 10-1 Mihogaoka, Ibaraki, Osaka, 567-0047, Japan.
Koichi FukaseDepartment of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka, 560-0043, Japan.
The University of Osaka · JP

Funding

Japan Society for the Promotion of Science JP18K07674Japan Society for the Promotion of Science JP20H00404Japan Society for the Promotion of Science JP20H05675Program on Open Innovation Platform with Enterprises, Research Institute and Academia JPMJOP1721
6 · The paper itself

Abstract

background

resultsAuNP with a diameter of 5, 13, 30, or 120 nm that had been modified with poly (ethylene glycol) methyl ether (mPEG) thiol and labeled with

conclusionsThe intratumoral single administration of a simple nanoparticle,

Indexed as

AnimalsAstatineGliomaGoldMaleMiceMice, Inbred BALB CMice, NudeNanoparticlesParticle SizePolyethylene GlycolsRadionuclide ImagingRatsStaining and LabelingTissue DistributionAstatineAstatine-211Goldmonomethoxypolyethylene glycolPolyethylene GlycolsAlpha emittersAstatine-211Cancer therapyGold nanoparticlesRadiolabeling

Identifiers

PMID34320997
PMCPMC8317303
OpenAlexW3159643917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.