Evidence map›Paper›PMID 34320990›Full record

ArticleEnvironmental health : a global access science source2021

Endocrine disrupting chemical-associated hair product use during pregnancy and gestational age at delivery: a pilot study.

Emma V Preston, Victoria Fruh, Marlee R Quinn, Michele R Hacker, Blair J Wylie, Karen O'Brien, Shruthi Mahalingaiah, Tamarra James-Todd

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

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  18. Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women's Health.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emma V Preston *Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA. epreston@hsph.harvard.edu.
Victoria Fruh *Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Marlee R QuinnDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Michele R HackerDepartment of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA.
Blair J WylieDepartment of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA.
Karen O'BrienDepartment of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA.
Shruthi Mahalingaiah *Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Tamarra James-Todd *Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Harvard University · USMassachusetts General Hospital · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Training Program in Environmental EpidemiologyT32ES007069 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LADEN, FRANCINE · 1985 to 2024
$13.9M
Phthalates, Gestational Diabetes, and Markers of Type 2 Diabetes Risk in WomenR01ES026166 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI JAMES-TODD, TAMARRA M · 2016 to 2021
$2.9M
NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES026166NIEHS NIH HHS T32 ES007069
6 · The paper itself

Abstract

backgroundPrenatal endocrine disrupting chemical (EDC) exposure has been associated with increased risk of preterm birth. Non-Hispanic Black women have higher incidence of preterm birth compared to other racial/ethnic groups and may be disproportionately exposed to EDCs through EDC-containing hair products. However, research on the use of EDC-associated hair products during pregnancy and risk of preterm birth is lacking. Therefore, the objective of this pilot study was to estimate associations of prenatal hair product use with gestational age at delivery in a Boston, Massachusetts area pregnancy cohort.

methodsThe study population consisted of a subset of participants enrolled in the Environmental Reproductive and Glucose Outcomes (ERGO) Study between 2018 and 2020. We collected self-reported data on demographics and hair product use using a previously validated questionnaire at four prenatal visits (median: 12, 19, 26, 36 weeks' gestation) and abstracted gestational age at delivery from medical records. We compared gestational age and hair product use by race/ethnicity and used linear regression to estimate covariate-adjusted associations of product use and frequency of use at each study visit with gestational age at delivery. Primary models were adjusted for maternal age at enrollment and delivery method.

resultsOf the 154 study participants, 7% delivered preterm. Non-Hispanic Black participants had lower mean gestational age at delivery compared to non-Hispanic White participants (38.2 vs. 39.2 weeks) and were more likely to report ever and more frequent use of hair products. In regression models, participants reporting daily use of hair oils at visit 4 had lower mean gestational age at delivery compared to non-users (β: -8.3 days; 95% confidence interval: -14.9, -1.6). We did not find evidence of associations at earlier visits or with other products.

conclusionsFrequent use of hair oils during late pregnancy may be associated with shorter gestational duration. As hair oils are more commonly used by non-Hispanic Black women and represent potentially modifiable EDC exposure sources, this may have important implications for the known racial disparity in preterm birth.

Indexed as

Endocrine DisruptorsHair PreparationsOilsAdultBlack or African AmericanBlack PeopleBostonCohort StudiesFemaleGestational AgeHumansMiddle AgedPilot ProjectsPregnancyPremature BirthWhite PeopleEndocrine DisruptorsHair PreparationsOilsEndocrine disrupting chemicalsHair productsPersonal care productsPregnancyPreterm birth

Identifiers

PMID34320990
PMCPMC8316883
OpenAlexW3183326050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.