Evidence map›Paper›PMID 34320841›Full record

Observational studyJournal of the American Heart Association2021

Incidence of Acute Myocardial Infarction in Northern Tanzania: A Modeling Approach Within a Prospective Observational Study.

Julian T Hertz, Deng B Madut, Matthew P Rubach, Gwamaka William, John A Crump, Sophie W Galson, Venance P Maro, Gerald S Bloomfield, Alexander T Limkakeng, Gloria Temu and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Acute coronary syndrome prevalence and outcomes in a Tanzanian emergency department: Results from a prospective surveillance study.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Evaluating the performance of the HEART score in a Tanzanian emergency department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2024
    Observational
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Julian T HertzDuke University School of Medicine Durham NC.
Deng B MadutDuke University School of Medicine Durham NC.
Matthew P RubachDuke University School of Medicine Durham NC.
Gwamaka WilliamKilimanjaro Christian Medical Centre Moshi Tanzania.
John A CrumpOtago Global Health Institute Dunedin New Zealand.
Sophie W GalsonDuke University School of Medicine Durham NC.
Venance P MaroKilimanjaro Christian Medical Centre Moshi Tanzania.
Gerald S BloomfieldDuke University School of Medicine Durham NC.
Alexander T LimkakengDuke University School of Medicine Durham NC.
Gloria TemuKilimanjaro Christian Medical Centre Moshi Tanzania.
Nathan M ThielmanDuke University School of Medicine Durham NC.
Francis M SakitaKilimanjaro Christian Medical Centre Moshi Tanzania.
Duke University · USKilimanjaro Christian Medical Centre · TZ

Funding

Vanderbilt-Emory-Cornell-Duke Global Health Fellowship Consortium-Expanding Diversity for Global Equity (EDGE)D43TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALIYU, MUKTAR HASSAN, HEIMBURGER, DOUGLAS CORBETT · 2017 to 2021
$6.3M
FIC NIH HHS D43 TW009337
6 · The paper itself

Abstract

Background Rigorous incidence data for acute myocardial infarction (AMI) in sub-Saharan Africa are lacking. Consequently, modeling studies based on limited data have suggested that the burden of AMI and AMI-associated mortality in sub-Saharan Africa is lower than in other world regions. Methods and Results We estimated the incidence of AMI in northern Tanzania in 2019 by integrating data from a prospective surveillance study (681 participants) and a community survey of healthcare-seeking behavior (718 participants). In the surveillance study, adults presenting to an emergency department with chest pain or shortness of breath were screened for AMI with ECG and troponin testing. AMI was defined by the Fourth Universal Definition of AMI criteria. Mortality was assessed 30 days following enrollment via in-person or telephone interviews. In the cluster-based community survey, adults in northern Tanzania were asked where they would present for chest pain or shortness of breath. Multipliers were applied to account for AMI cases that would have been missed by our surveillance methods. The estimated annual incidence of AMI was 172 (207 among men and 139 among women) cases per 100 000 people. The age-standardized annual incidence was 211 (263 among men and 170 among women) per 100 000 people. The estimated annual incidence of AMI-associated mortality was 87 deaths per 100 000 people, and the age-standardized annual incidence was 102 deaths per 100 000 people. Conclusions The incidence of AMI and AMI-associated mortality in northern Tanzania is much higher than previously estimated and similar to that observed in high-income countries.

Indexed as

Myocardial InfarctionEmergency Service, HospitalFemaleHumansIncidenceMaleMiddle AgedMortalityPatient Acceptance of Health CarePopulation SurveillanceSurveys and QuestionnairesSymptom AssessmentTanzaniaincidencemortalitymyocardial infarctionsub‐Saharan AfricaTanzania

Identifiers

PMID34320841
PMCPMC8475708
OpenAlexW3186371915

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.