ArticleRevista da Sociedade Brasileira de Medicina Tropical2021
Clinical aspects of human rabies in the state of Ceará, Brazil: an overview of 63 cases.
Article in Revista da Sociedade Brasileira de Medicina Tropical, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Dog bite-associated pathogens: advances in pathogenic mechanisms and systemic clinical consequences in humans.One health (Amsterdam, Netherlands) · 2026Review
- Application of Probe-Capture metagenomics in rabies diagnosis.Virology journal · 2025Article
- Microbes and Mental Illness: Past, Present, and Future.Healthcare (Basel, Switzerland) · 2023Review
- Rabies in the Tropics.Current tropical medicine reports · 2022Review
- Knowledge, Attitudes and Practices Regarding Sylvatic Rabies among High-Risk Households in Ceará State, Brazil.Tropical medicine and infectious disease · 2021Article
- Clinical aspects of human rabies in the state of Ceará, Brazil: an overview of 63 cases.Revista da Sociedade Brasileira de Medicina TropicalReview
- Rabies immunoglobulin should not be forgotten in category III exposure.Revista da Sociedade Brasileira de Medicina TropicalArticle
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRabies is considered one of the most relevant public health problems owing to its high fatality rate and the high number of deaths worldwide.
methodsWe included patients with human rabies who attended a reference hospital in the state of Ceará during 1976-2019.
resultsData were available for 63 out of 171 (36.8%) patients. Of these patients, 48 (76.2%) were attacked by dogs. In recent years, wild animals have been the most common aggressor species (marmosets and bats). Only 39 (70%) patients were initially correctly suspected with rabies. Bites were the most frequent exposure (56; 96%), most commonly on the hands (21; 42%) and the head (9; 18.4%). Only 14 (22%) patients had sought medical assistance before the onset of symptoms, and only one completed post-exposure prophylaxis. The most prevalent signs and symptoms included aggressiveness/irritability (50; 79.4%), fever (42; 66.7%), sore throat/dysphagia (40; 63.5%), and myalgia (28; 44.4%). Hydrophobia was present in 17 patients (22.0%).
conclusionsMost cases of human rabies in Ceará occurred due to the failure to seek medical assistance and/or the failure of the health system in initiating early post-exposure prophylaxis. There is a need for specific information and education campaigns focusing on the cycle of sylvatic rabies as well as prevention measures. Health professionals should undergo refresher training courses on the signs and symptoms of rabies and on the specific epidemiological features of the disease in Brazil.
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