Evidence map›Paper›PMID 34319809›Full record

ArticleApplied and environmental microbiology2021

Outer Membrane Vesicles Derived from

Huizhen Tian, Biaoxian Li, Tian Xu, Haolin Yu, Jingxuan Chen, Haiyan Yu, Shan Li, Lingbing Zeng, Xiaotian Huang, Qiong Liu

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Adjuvants forVirulence · 2024
    Review
  14. Article
  15. Review
  16. Outer Membrane Vesicle Vaccine Platforms.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Review
  17. Article
  18. Article
  19. The Diversity ofMicroorganisms · 2023
    Review
  20. Opportunities for engineering outer membrane vesicles using synthetic biology approaches.Extracellular vesicles and circulating nucleic acids · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Huizhen TianDepartment of Medical Microbiology, School of Medicine, Nanchang Universitygrid.260463.5, Nanchang, China.
Biaoxian LiDepartment of Medical Microbiology, School of Medicine, Nanchang Universitygrid.260463.5, Nanchang, China.
Tian XuDepartment of Medical Microbiology, School of Medicine, Nanchang Universitygrid.260463.5, Nanchang, China.
Haolin YuSchool of Ophthalmology and Optometry, Nanchang Universitygrid.260463.5, Nanchang, China.
Jingxuan ChenSchool of Ophthalmology and Optometry, Nanchang Universitygrid.260463.5, Nanchang, China.
Haiyan YuDepartment of Medical Microbiology, School of Medicine, Nanchang Universitygrid.260463.5, Nanchang, China.
Shan LiDepartment of Medical Microbiology, School of Medicine, Nanchang Universitygrid.260463.5, Nanchang, China.
Lingbing ZengThe First Affiliated Hospital of Nanchang Universitygrid.260463.5, Nanchang, China.
Xiaotian HuangDepartment of Medical Microbiology, School of Medicine, Nanchang Universitygrid.260463.5, Nanchang, China.
Qiong LiuDepartment of Medical Microbiology, School of Medicine, Nanchang Universitygrid.260463.5, Nanchang, China.ORCID 0000-0002-8950-6133
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shigellosis has become a serious threat to health in many developing countries due to the severe diarrhea it causes. Shigella flexneri 2a is the principal species responsible for this endemic disease. Despite multiple attempts to design a vaccine against shigellosis, no effective vaccine has been developed yet. Lipopolysaccharide (LPS) is both an essential virulence factor and an antigen protective against

Indexed as

Bacterial Outer MembraneSalmonella typhimuriumAnimalsCell ProliferationCytokinesDysentery, BacillaryFemaleLymphocytesMiceMice, Inbred BALB CO AntigensShigella flexneriShigella VaccinesSpleenCytokinesO AntigensShigella VaccinesO-polysaccharide antigenouter membrane vesicleSalmonella TyphimuriumShigella flexneri 2a

Identifiers

PMID34319809
PMCPMC8432525
OpenAlexW3186637192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.