ArticleInvestigative ophthalmology & visual science2021
Differences in Retinal and Choroidal Vasculature and Perfusion Related to Axial Length in Pediatric Anisomyopes.
Article in Investigative ophthalmology & visual science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 75 citations in OpenAlex.
- Short-term effects of sunlight exposure on fundus blood flow perfusion in children: a randomised controlled trial.The British journal of ophthalmology · 2024Trial
- Potential Choroidal Mechanisms Underlying Atropine's Antimyopic and Rebound Effects: A Mediation Analysis in a Randomized Clinical Trial.Investigative ophthalmology & visual science · 2023Trial
- Impact of Optical Coherence Tomography Scan Pattern and Chorio-Scleral Interface Delineation on Choroidal Vascularity Index Measurements.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Short-Term Effects of Orthokeratology Treatment Zone Decentration on Choroidal Thickness and Vasculature.Translational vision science & technology · 2026Article
- Retinal Microvascular Dysfunction Reflects Vascular and Alzheimer's-Related Pathology in Dementia With Lewy Bodies.CNS neuroscience & therapeutics · 2026Article
- Biphasic Change in Retinal Arterial Hemodynamics Amidst Systematic Perfusion Decline With Increasing Degree of Myopia.Investigative ophthalmology & visual science · 2026Article
- Peripheral Retinal Vessel Density in Children and Adolescents with Myopia: A Deep Learning Assessment.Ophthalmology and therapy · 2026Article
- A bibliometric and visualized analysis of choriocapillaris from 2013 to 2023.International journal of ophthalmology · 2026Article
- Retinal and Choroidal Microvasculature at Different Myopia Severities: A Systematic Review and Meta-Analysis.Ophthalmology science · 2026Review
- Repeatability, reproducibility, and agreement regarding measurement of choroidal vascularity index between OCT and OCT angiography.International journal of ophthalmology · 2026Article
- Retinal microvascular alterations reflect cerebral small vessel disease burden in frontotemporal dementia: a multimodal OCTA-MRI Study.Alzheimer's research & therapy · 2025Article
- Apolipoprotein E ε4 homozygosity exacerbates retinal and cerebral microvascular dysfunction in Alzheimer's disease: A mediation analysis of vascular contributions to cognitive decline.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Swept-Source OCT Angiography-Derived Regional Normative Data of Peripapillary Vessel Density in Healthy Populations.Translational vision science & technology · 2025Article
- Choroidal Features of Cynomolgus Macaques in Relation to Age and Axial Length.Investigative ophthalmology & visual science · 2025Article
- Assessment of choriocapillary flow deficits in myopic children by optical coherence tomography angiography.Scientific reports · 2025Article
- Age-Related Regional Changes in Choroidal Vascularity in Healthy Emmetropic Eyes.Translational vision science & technology · 2025Article
- Changes in Retinal Oxygen Saturation 1 Month After Femtosecond LASIK Treatment in Chinese Adults with Myopia.Ophthalmology and therapy · 2025Article
- Interocular differences in choroidal thickness and circulation in anisomyopic adults and their association with myopia severity.Frontiers in medicine · 2025Article
- Biometric parameters and choroidal microstructure in Chinese children with unilateral anisometropia.Frontiers in medicine · 2025Article
- Relationship between the morphology of the posterior pole of the eyeball and changes in choroidal structure and blood flow in myopia.Quantitative imaging in medicine and surgery · 2024Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The purpose of this study was to evaluate the interocular differences in choroidal vasculature, choriocapillaris perfusion, and retinal microvascular network, and to explore their associations with interocular asymmetry in axial lengths (ALs) in children with anisomyopia. Methods: Refractive error, AL, and other biometric parameters were measured in 70 children with anisomyopia. Using optical coherence tomography (OCT) and OCT-angiography, we measured the submacular choroidal thickness (ChT), total choroidal area (TCA), luminal area (LA), stromal area (SA), choroidal vascularity index (CVI), choriocapillaris flow deficit (CcFD), retinal vessel density (VD), and foveal avascular zone (FAZ) area. Results: The mean interocular differences in spherical equivalent refraction and AL were -2.26 ± 0.94 diopters and 0.95 ± 0.46 mm, respectively. Submacular ChT, TCA, LA, SA, and CVI were all significantly lower in the more myopic (longer AL) eyes than in the less myopic (shorter AL) fellow eyes. In eyes with longer ALs, both the CcFD and FAZ areas were significantly greater, whereas the superficial and deep retinal VDs were significantly less. After adjusting for corneal power and intraocular pressure, interocular differences in LA (β = -0.774), SA (β = -0.991), and CcFD (β = 0.040) were significantly associated with interocular asymmetry in AL (all P < 0.05). Conclusions: In pediatric anisomyopes, eyes with longer ALs tended to have lower choroidal vascularity and choriocapillaris perfusion than the contralateral eyes with shorter ALs. Longitudinal investigations would be useful follow-ups to test for a causal role of choroidal circulation in human myopia.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.