Evidence map›Paper›PMID 34319248›Full record

ArticleJMIR research protocols2021

Safety and Acceptability of a Natural Language Artificial Intelligence Assistant to Deliver Clinical Follow-up to Cataract Surgery Patients: Proposal.

Nick de Pennington, Guy Mole, Ernest Lim, Madison Milne-Ives, Eduardo Normando, Kanmin Xue, Edward Meinert

Registry-linked trialAbstract read
In one paragraph

Article in JMIR research protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05213390 (A Clinical Investigation of an Autonomous Phone Conversational Agent for Cataract Surgery Follow-up), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05213390 nacompletednot on this map

A Clinical Investigation of an Autonomous Phone Conversational Agent for Cataract Surgery Follow-up

TypeinterventionalSponsorUniversity of PlymouthRan2021 to 2022Enrolled225ConditionsCataract, After CataractArmsDora
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
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  5. Mapping the Process of Engagement With Digital Health Interventions: A Cross-Case Synthesis.Mayo Clinic proceedings. Innovations, quality & outcomes · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nick de PenningtonUfonia Ltd, Oxford, United Kingdom.ORCID https://orcid.org/0000-0003-4536-4978
Guy MoleUfonia Ltd, Oxford, United Kingdom.ORCID https://orcid.org/0000-0002-9184-2531
Ernest LimUfonia Ltd, Oxford, United Kingdom.ORCID https://orcid.org/0000-0002-6972-0511
Madison Milne-IvesCentre for Health Technology, University of Plymouth, Plymouth, United Kingdom.ORCID https://orcid.org/0000-0001-7628-882X
Eduardo NormandoImperial College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-5774-8082
Kanmin XueUniversity of Oxford, Oxford, United Kingdom.ORCID https://orcid.org/0000-0003-0065-9131
Edward MeinertCentre for Health Technology, University of Plymouth, Plymouth, United Kingdom.ORCID https://orcid.org/0000-0003-2484-3347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to an aging population, the demand for many services is exceeding the capacity of the clinical workforce. As a result, staff are facing a crisis of burnout from being pressured to deliver high-volume workloads, driving increasing costs for providers. Artificial intelligence (AI), in the form of conversational agents, presents a possible opportunity to enable efficiency in the delivery of care.

objectiveThis study aims to evaluate the effectiveness, usability, and acceptability of Dora agent: Ufonia's autonomous voice conversational agent, an AI-enabled autonomous telemedicine call for the detection of postoperative cataract surgery patients who require further assessment. The objectives of this study are to establish Dora's efficacy in comparison with an expert clinician, determine baseline sensitivity and specificity for the detection of true complications, evaluate patient acceptability, collect evidence for cost-effectiveness, and capture data to support further development and evaluation.

methodsUsing an implementation science construct, the interdisciplinary study will be a mixed methods phase 1 pilot establishing interobserver reliability of the system, usability, and acceptability. This will be done using the following scales and frameworks: the system usability scale; assessment of Health Information Technology Interventions in Evidence-Based Medicine Evaluation Framework; the telehealth usability questionnaire; and the Non-Adoption, Abandonment, and Challenges to the Scale-up, Spread and Suitability framework.

resultsThe evaluation is expected to show that conversational technology can be used to conduct an accurate assessment and that it is acceptable to different populations with different backgrounds. In addition, the results will demonstrate how successfully the system can be delivered in organizations with different clinical pathways and how it can be integrated with their existing platforms.

conclusionsThe project's key contributions will be evidence of the effectiveness of AI voice conversational agents and their associated usability and acceptability. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/27227.

Indexed as

aftercareartificial intelligencecataractcell phonechatbotconversational agentdelivery of health caredialogue systemexpert systemshealth communicationhealth servicesinternetmedical informaticsmental healthnatural language processingpatient acceptance of health carerelational agentspeech recognition softwaretelemedicine

Identifiers

PMID34319248
PMCPMC8367096

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.