Evidence map›Paper›PMID 34319020›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2021

MELD-Sarcopenia is Better than ALBI and MELD Score in Patients with Hepatocellular Carcinoma Awaiting Liver Transplantation.

Ayman Alsebaey, Aliaa Sabry, Hanaa Said Rashed, Maha Mohammad Elsabaawy, Amr Ragab, Rasha Abdelhafiz Aly, Hanaa Badran

Open access · goldAbstract read
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ayman AlsebaeyDepartment of Hepatology and Gastroenterology, National Liver Institute, Menoufia University, Egypt.ORCID 0000-0003-3781-2312
Aliaa SabryDepartment of Hepatology and Gastroenterology, National Liver Institute, Menoufia University, Egypt.
Hanaa Said RashedDepartment of Anesthesia, National Liver Institute, Menoufia University, Shebeen El-Koom, Egypt.ORCID 0000-0001-7810-9610
Maha Mohammad ElsabaawyDepartment of Hepatology and Gastroenterology, National Liver Institute, Menoufia University, Egypt.ORCID 0002-3110-1547
Amr RagabDepartment of Hepatology and Gastroenterology, National Liver Institute, Menoufia University, Egypt.
Rasha Abdelhafiz AlyDepartment of Diagnostic Medical Imaging and Interventional Radiology, National Liver Institute, Menoufia University, Shebeen El-Koom, Egypt.
Hanaa BadranDepartment of Hepatology and Gastroenterology, National Liver Institute, Menoufia University, Egypt.
Menoufia University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe albumin bilirubin (ALBI) score and model of end stage liver disease (MELD) are prognostic in patients with hepatocellular carcinoma (HCC). Aim was to compare MELD-sarcopenia to MELD and ALBI scores in patients with HCC awaiting liver transplantation.

methodspatients with HCC (n=262) were included and followed up for 12 months. Baseline MELD, ALBI and MELD-sarcopenia models were calculated.

resultsThe average age was 59.61 ±8.09 years. Most patients were males (69.5%), CTP class A (55.7%) and BCLC stage B (54.2%). Hepatitis C virus was the main cause of liver cirrhosis in most patients (88.9%). The average MELD, MELD-sarcopenia and median ALBI score were 10.65 ±2.54, 15.11 ±6.22 and -2.12 (0.74) respectively. Sarcopenia patients had higher MELD, ALBI and MELD-sarcopenia values. Patients with sarcopenia had lower survival (10.09 months) than those without (11.72 months). The ALBI, MELD and MELD-sarcopenia were associated with mortality. ALBI had AUROC of 0.717 (95% CI: 0.659 - 0.771), MELD had AUROC of 0.656 (95% CI: 0.595 - 0.713) and MELD-sarcopenia had AUROC of 0.798 (95% CI: 0.744 - 0.845). The ALBI and MELD scores had comparable AUROC (p=0.081). The MELD-sarcopenia had superior AUROC than MELD (p=0.001) and ALBI (p=0.05).

conclusionMELD-sarcopenia is better prognostic model than the ALBI and MELD scores in HCC patients awaiting liver transplantation.<br />.

Indexed as

BilirubinBiomarkersCarcinoma, HepatocellularFemaleHumansLiver NeoplasmsLiver TransplantationMaleMiddle AgedPredictive Value of TestsPrognosisSarcopeniaSerum AlbuminBilirubinBiomarkersSerum AlbuminALBIHepatocellular carcinomaMELDMELD-sarcopeniasarcopenia

Identifiers

PMID34319020
PMCPMC8607083
OpenAlexW3184481542

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.