Evidence map›Paper›PMID 34319018›Full record

SynthesisAsian Pacific journal of cancer prevention : APJCP2021

Breast Cancer Risk From Modifiable and Non-Modifiable Risk Factors among Palestinian Women: A Systematic Review and Meta-Analysis.

Heba Mohammed Arafat, Julia Omar, Rosediani Muhamad, Tengku Ahmad Damitri Al-Astani, Noorazliyana Shafii, Nahed Ali Al Laham, Ihab Naser, Ohood Mohammed Shamallakh, Kholoud Mohammed Shamallakh, Majed Abed Al Rahman Jebril

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Asian Pacific journal of cancer prevention : APJCP, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 5 pooled it
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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  4. Systematic Review and Meta-Analysis of Lifestyle and Reproductive Factors Associated with Risk of Breast Cancer in Asian Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Heba Mohammed ArafatDepartment of Chemical Pathology, School of Medical Sciences, Health Campus, University Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.ORCID 0000-0003-2710-5673
Julia OmarDepartment of Chemical Pathology, School of Medical Sciences, Health Campus, University Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
Rosediani MuhamadDepartment of Family Medicine, School of Medical Sciences, Health Campus, University Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
Tengku Ahmad Damitri Al-AstaniDepartment of Chemical Pathology, School of Medical Sciences, Health Campus, University Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.ORCID 0000-0003-3265-1679
Noorazliyana ShafiiDepartment of Chemical Pathology, School of Medical Sciences, Health Campus, University Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
Nahed Ali Al LahamDepartment of Laboratory Medicine, Al Azhar University-Gaza, Gaza Strip, Palestine.
Ihab NaserDepartment of Clinical Nutrition, Faculty of Applied Medical Sciences, Al- Azhar University- Gaza, Gaza City, Palestine.
Ohood Mohammed ShamallakhDepartment of a Medical Laboratory Sciences, Faculty of Health Sciences, Islamic University of Gaza, Gaza City, Palestine.
Kholoud Mohammed ShamallakhDepartment of a Medical Laboratory Sciences, Faculty of Health Sciences, Islamic University of Gaza, Gaza City, Palestine.
Majed Abed Al Rahman JebrilGlobal Health Institute, School of Public Health, Xi'an Jiaotong University, Health Science Center, Xi'an, Shaanxi, China.
Islamic University of Gaza · PSAl-Azhar University – Gaza · PS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBreast cancer (BC) is known as one of the deadliest forms of cancer, and it is increasing globally. Identifying risk factors for BC is a key point in developing preventive strategies to reduce its occurrence. Herein, we aimed to conduct a systematic review and meta-analysis focus on the risk factors for BC in Palestine. MATERIAL AND

methodsWe performed a systematic search via PubMed, MEDLINE, SCOPUS, Science Direct, Cochrane library, Emerald Insight, and Google scholar for identifying studies published on BC risk factors up to March 2021. Pooled odds ratios (OR) are calculated using fixed and random-effect models. Data were processed using Review Manager 5.4 (RevMan 5.4).

resultsFrom a total of 73 articles, seven case-control studies met the criteria for systematic review. Meta-analysis results showed that of the known modifiable risk factors for BC, diabetes mellitus (DM) had the highest odds ratio (OR = 4.97, 95% CI 3.00- 8.25) followed by hypertension (OR = 3.21, 95% CI 1.96-5.23), obesity (BMI >30 Kg/m2) (OR = 2.90, 95% CI 2.00- 4.21), and passive smoking (OR = 1.50, 95% CI 1.12- 2.02). Controversially, breastfeeding (OR = 0.37, 95% CI 0.23- 0.61) was protective factor in BC. Of non-modifiable risk factors for BC has reached menopause had the highest odds ratio (OR = 3.74, 95% CI 2.64- 5.29), followed by family history of BC (OR = 2.63, 95% CI 1.07-6.44) and age (≥ 40 years) (OR = 2.49, 95% CI 1.43-4.34).

conclusionsThe most significant predictors of BC in Palestine were DM, hypertension, passive smokers, age (>40), reached menopause, and family history of BC. Almost all these risk factors are consistent with known risk factors for breast cancer in other parts of the world.<br />.

Indexed as

ArabsAge FactorsBreast NeoplasmsFemaleHumansRisk Factorsbreast cancerMeta-analysisPalestinian womenrisk factors

Identifiers

PMID34319018
PMCPMC8607101
OpenAlexW3186693250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.