Evidence map›Paper›PMID 34318996›Full record

ArticleJournal of applied clinical medical physics2021

Automated treatment planning of prostate stereotactic body radiotherapy with focal boosting on a fast-rotating O-ring linac: Plan quality comparison with C-arm linacs.

Robin De Roover, Wouter Crijns, Kenneth Poels, Bertrand Dewit, Cédric Draulans, Karin Haustermans, Tom Depuydt

Open access · goldAbstract read
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Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Robin De RooverDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0001-7452-7073
Wouter CrijnsDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
Kenneth PoelsDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
Bertrand DewitDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
Cédric DraulansDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
Karin HaustermansDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
Tom DepuydtDepartment of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.
KU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe integration of auto-segmentation and automated treatment planning methods on a fast-rotating O-ring linac may improve the time efficiency of online adaptive radiotherapy workflows. This study investigates whether automated treatment planning of prostate SBRT with focal boosting on the O-ring linac could generate plans that are of similar quality as those obtained through manual planning on clinical C-arm linacs.

methodsFor 20 men with prostate cancer, reference treatment plans were generated on a TrueBeam STx C-arm linac with HD120 MLC and a TrueBeam C-arm linac with Millennium 120 MLC using 6 MV flattened dual arc VMAT. Manual planning on the Halcyon fast-rotating O-ring linac was performed using 6 MV FFF dual arc VMAT (HA2-DL10) and triple arc VMAT (HA3-DL10) to investigate the performance of the dual-layer MLC system. Automated planning was performed for triple arc VMAT on the Halcyon linac (ET3-DL10) using the automated planning algorithms of Ethos Treatment Planning. The prescribed dose was 35 Gy to the prostate and 30 Gy to the seminal vesicles in five fractions. The iso-toxic focal boost to the intraprostatic tumor nodule(s) was aimed to receive up to 50 Gy. Plan deliverability was verified using portal image dosimetry measurements.

resultsCompared to the C-arm linacs, ET3-DL10 shows increased seminal vesicles PTV coverage (D

conclusionsAutomated planning of prostate SBRT with focal boosting on the fast-rotating O-ring linac is feasible and achieves similar plan quality as those obtained on clinical C-arm linacs using manual planning.

Indexed as

RadiosurgeryRadiotherapy, Intensity-ModulatedHumansMaleProstateRadiotherapy DosageRadiotherapy Planning, Computer-Assistedautomationfocal boostO-ring linacplan qualityprostate cancerSBRT

Identifiers

PMID34318996
PMCPMC8425873
OpenAlexW3186878025

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.