Evidence map›Paper›PMID 34318727›Full record

ArticleGlobal spine journal2023

Impact of Racial Disparities on All-Cause Mortality in Patients With Tumors of the Spinal Cord or Spinal Meninges: A Propensity-Score Analysis.

Aladine A Elsamadicy, Isaac Freedman, Andrew B Koo, Wyatt B David, Benjamin C Reeves, Astrid Hengartner, Zach Pennington, Maxwell Laurans, Luis Kolb, John H Shin and 1 more

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Aladine A ElsamadicyDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-7658-6461
Isaac FreedmanDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-2603-4201
Andrew B KooDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
Wyatt B DavidDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
Benjamin C ReevesDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
Astrid HengartnerDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-0887-6851
Zach PenningtonDepartment of Neurosurgery, John Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-8012-860X
Maxwell LauransDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
Luis KolbDepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
John H ShinDepartment of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Daniel SciubbaDepartment of Neurosurgery, John Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-7604-434X
Yale University · USHarvard University · USJohns Hopkins University · USNorthwell Health · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Short-Term Reserch Training: Students in Health SchoolsT35HL007649 · NHLBI · YALE UNIVERSITY · PI Sarwat I Chaudhry, Erica L Herzog · 1987 to 2026
$5.7M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS T35 HL007649
6 · The paper itself

Abstract

STUDY

designRetrospective cohort study.

objectiveThe influence that race has on mortality rates in patients with spinal cord tumors is relatively unknown. The aim of this study was to investigate the influence of race on the outcomes of patients with primary malignant or nonmalignant tumors of the spinal cord or spinal meninges.

methodsThe Surveillance, Epidemiology, and End Results (SEER) Registry was used to identify all patients with a code for primary malignant or nonmalignant tumor of the spinal cord (C72.0) or spinal meninges (C70.1) from 1973 through 2016. Racial groups (African-American/Black vs. White) were balanced using propensity-score (PS) matching using a non-parsimonious 1:1 nearest neighbor matching algorithm. Overall survival (OS) estimates were obtained using the Kaplan-Meier method and compared across non-PS-matched and PS-matched groups using log-rank tests. Associations of survival with clinical variables was assessed using doubly robust Cox proportional-hazards (CPH) regression analysis.

resultsThere were a total of 7,498 patients identified with 648 (6.8%) being African American. African-American patients with primary intradural spine tumors were more likely to die of all causes than were White patients in both the non-PS-matched [HR: 1.26, 95% CI: (1.04, 1.51),

conclusionsOur study provides population-based estimates of the prognosis for patients with primary malignant or nonmalignant tumors of the spinal cord or spinal meninges and suggests that race may impact all-cause mortality.

Indexed as

disparitieshealthcaremortalityoncologyracetumor

Identifiers

PMID34318727
PMCPMC10416582
OpenAlexW3186889691

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.