Evidence map›Paper›PMID 34318709›Full record

ArticleCell transplantation

Effects of UCMSCs Delivered through Different Transplantation Approaches on Acute Radiation Enteritis in Rats.

Jun Li, Yinghong Jiang, Hua Yu, Lejiang Liu, Qiang Wang, Hongpin Ju, Xuemei Zhang, Wenqi Wang, Xudong Yin, Qiong Wu and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Jun LiMedical School of Ningde Normal University, Ningde, China.ORCID 0000-0002-2972-856X
Yinghong JiangMedical School of Kunming University, Kunming, China.
Hua YuMedical School of Kunming University, Kunming, China.
Lejiang LiuMedical School of Kunming University, Kunming, China.
Qiang WangCell Biological Therapy Center, and Transfer Medicine Key Laboratory of Cell Therapy Technology of Yunan Province, and National and Local Joint Engineering Laboratory of Stem Cell and Immunocyte Biomedical Technology, 920th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Kunming, China.
Hongpin JuMedical School of Kunming University, Kunming, China.
Xuemei ZhangMedical School of Kunming University, Kunming, China.
Wenqi WangMedical School of Kunming University, Kunming, China.
Xudong YinSchool of Agriculture and Life Science, Kunming University, Kunming, China.
Qiong WuSchool of Chemistry and Chemical Engineering, Kunming University, Kunming, China.
Jianzhong XiaoMedical School of Ningde Normal University, Ningde, China.
Jianrong MiaoMedical School of Ningde Normal University, Ningde, China.
Xiao YeMedical School of Ningde Normal University, Ningde, China.
Tianyu LiClass 1, Grade 2019, postgraduate student majoring in physics, School of Physical Science and Technology, Kunming University, Kunming, China.
Hui TianClass 1, Grade 2018, Undergraduate majoring in chemistry teacher education, School of Chemistry and Chemical Engineering, Kunming University, Kunming, China.
Wei XueMedical School of Kunming University, Kunming, China.
Kunming University · CNNingde Normal University · CNCell Technology (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation enteritis is the most common and serious complication of abdominal or pelvic radiation therapy. Mesenchymal stem cells (MSCs), as well as cell protection agents, inhibit apoptosis and promote the proliferation of injured tissues. 3 human umbilical cords MSCs (UCMSCs) were injected into the tail vein or peritoneal cavity of a rat model of radiation enteritis. The temporary protective effect was assessed by identification of donor cells, detection of cellular immune parameters and inflammatory cytokine levels, quantitation of jejunum mucosal preservation and examination of the rat remaining life. Only the rats in the intraperitoneal injection group exhibited a few positive donor cells 7 days after transplantation. CD

Indexed as

Acute DiseaseAnimalsDisease Models, AnimalEnteritisFemaleHumansMesenchymal Stem Cell TransplantationRatsUmbilical Cordacute radiation enteritisintraperitoneal injectionUCMSCs

Identifiers

PMID34318709
PMCPMC8323445
OpenAlexW3183196789

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.