ArticleVeterinary medicine and science2021
Comparative transcriptomic analysis of ovaries from high and low egg-laying Lingyun black-bone chickens.
Article in Veterinary medicine and science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 18 citations in OpenAlex.
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- Insulin-like growth factor-1 is involved in the deteriorated performance of aged laying hens.Journal of animal science · 2022Article
- Comparative transcriptome analysis of Indian domestic duck reveals candidate genes associated with egg production.Scientific reports · 2022Article
- Ovarian Transcriptomic Analysis of Ninghai Indigenous Chickens at Different Egg-Laying Periods.Genes · 2022Article
- Comparative transcriptomic analysis of ovaries from high and low egg-laying Lingyun black-bone chickens.Veterinary medicine and science · 2021Article
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7 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Egg-laying rate is mainly determined by ovarian function and regulated by the hypothalamic-pituitary-gonadal axis; however, the mechanism by which the ovary regulates the egg-laying rate is still poorly understood. The purpose of this study was to compare the differences in the transcriptomes of the ovary of Lingyun black-bone chickens with relatively high and low egg-laying rates and screen candidate genes related to the egg-laying rate. RNA-sequencing (RNA-Seq) was conducted to explore the chicken transcriptome from the ovarian tissue of six Lingyun black-bone chickens with high (group G, n = 3) and low (group D, n = 3) egg-laying rates. The results showed that 235 differentially expressed genes (DEGs) were identified between the chickens with high and low egg-laying rates; among them, 209 DEGs were up-regulated and 26 DEGs were down-regulated. Gene Ontology analysis showed that the up-regulated 209 DEGs were enriched in 50 GO terms and the down-regulated 26 DEGs were enriched in 40 GO terms. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that up-regulated DEGs were significantly enriched in 25 pathways and down-regulated DEGs were significantly enriched in three pathways. Among the pathways, we found the longevity regulating pathway-multiple species pathway, Estrogen signalling pathway and PPAR signalling pathway may have an essential function in regulating the egg-laying rate. The results highlighted DEGs in the ovarian tissues of relatively high and low laying Lingyun black-bone chicken and identified essential candidate genes related to the egg-laying rate, thereby providing a theoretical basis for improving the egg-laying rate of Lingyun black-bone chicken.
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