ArticleIndian journal of pediatrics2022
Threshold of Inotropic Score and Vasoactive-Inotropic Score for Predicting Mortality in Pediatric Septic Shock.
Article in Indian journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Vaso-active inotropic scores: Clinical value, pros and cons.JHLT open · 2026Article
- Vasoactive-inotropic score as a predictor of clinical deterioration in pediatric patients undergoing venovenous extracorporeal membrane oxygenation: a preliminary single-center study in South Korea.Acute and critical care · 2026Article
- Prognostic value of cardiac biomarkers and Phoenix criteria in pediatric sepsis: a retrospective cohort study.BMC pediatrics · 2025Article
- Vasoactive-Inotropic Score (VIS) and Outcome of Children with Pediatric Septic Shock.Indian pediatrics · 2025Observational
- Outcomes of continuous kidney replacement therapy in pediatric patients: the impact of timing and predictors of mortality.Pediatric nephrology (Berlin, Germany) · 2025Article
- Development and Validation of a Minimum Dataset for a Pediatric Septic Shock Registry: A Descriptive and Cross-Sectional Study.Health science reports · 2025Article
- A new mortality score in preterm infants: the vasoactive inotropic score.BMC pediatrics · 2025Article
- Comparing the clinical characteristics and risk factors of prognosis in pediatric ARDS with and without malignancies: a retrospective cohort study.BMC pulmonary medicine · 2025Article
- Vasoactive Inotrope Score as a Predictor of Postoperative Complications in Cancer Surgery Patients-A Prospective Observational Study.Indian journal of surgical oncology · 2024Article
- Clinical characteristics and mortality risk factors of premature infants with carbapenem-resistant Klebsiella pneumoniae bloodstream infection.Scientific reports · 2024Article
- Blood pressure response index and clinical outcomes in patients with septic shock: a multicenter cohort study.EBioMedicine · 2024Article
- Prognostic implication of Vasoactive Inotropic Score in adult patients with cardiogenic shock on veno-arterial extracorporeal membrane oxygenation.Journal of thoracic disease · 2024Article
- Prognostic evaluation of the norepinephrine equivalent score and the vasoactive-inotropic score in patients with sepsis and septic shock: a retrospective cohort study.Frontiers in cardiovascular medicine · 2024Article
- Tendency of dynamic vasoactive and inotropic medications data as a robust predictor of mortality in patients with septic shock: An analysis of the MIMIC-IV database.Frontiers in cardiovascular medicine · 2023Article
- Vasoactive-Inotropic Score: An Objective Indicator of Cardiovascular Dysfunction in Children with Septic Shock?Indian journal of pediatrics · 2022Article
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6 authors.
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Abstract
objectiveTo determine the threshold of the inotropic score (IS) and vasoactive-inotropic score (VIS) for predicting mortality in pediatric septic shock.
methodThis retrospective cohort study included children aged 1 mo to 13 y with septic shock, requiring vasoactive medication. The area under curve receiver operating characteristic (AUROC) was calculated using mean IS and mean VIS to predict PICU mortality, and Youden index cut points were generated. Sensitivity, specificity, and binary regression analysis were performed.
resultsA total of 176 patients were enrolled (survivor, n = 72, 41% and nonsurvivor, n = 104, 59%). For predicting the PICU mortality, AUROC (95% CI) of IS was 0.80 (0.74-0.86) [sensitivity of 88.5 (80.7-94) and specificity of 58.3 (46.1-69.8)] and AUROC of VIS was 0.88 (0.82-0.92) [sensitivity of 83.7 (75.1-90.2) and specificity of 80.6 (69.5-89)]. The respective cutoff scores of IS and VIS were 28 and 42.5. On regression analysis (adjusted odds ratio, 95% CI), illness severity (PRISM-III) (1.12, 1.05-1.12), worst lactate value (1.31, 1.08-1.58), IS (> 28) (3.98, 1.24-12.80), and VIS (> 42.5) (4.66, 1.57-13.87) independently predicted the PICU mortality (r
conclusionThreshold of inotropic score (> 28) and vasoactive-inotropic score (> 42.5) were independently associated with PICU mortality. In addition to IS and VIS, severity and worst lactate value independently predicted septic shock mortality in PICU.
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