Evidence map›Paper›PMID 34318357›Full record

ArticleJournal of cancer research and clinical oncology2021

Relationship between lung function and lung cancer risk: a pooled analysis of cohorts plus Mendelian randomization study.

Zixuan Su, Yu Jiang, Caichen Li, Ran Zhong, Runchen Wang, Yaokai Wen, Hengrui Liang, Zhuxing Chen, Jianxing He, Wenhua Liang

Abstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zixuan SuDepartment of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Yu JiangDepartment of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Caichen LiDepartment of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Ran ZhongDepartment of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Runchen WangDepartment of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Yaokai WenDepartment of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Hengrui LiangDepartment of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Zhuxing ChenDepartment of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Jianxing He *Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China. drjianxing.he@gmail.com.ORCID http://orcid.org/0000-0003-1737-8192
Wenhua Liang *Department of Thoracic Surgery and Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China. liangwh1987@163.com.

Funding

China National Science Foundation 81501996China National Science Foundation 81871893High-level university construction project of Guangzhou Medical University 201715907High-level university construction project of Guangzhou Medical University 2017160107High-level university construction project of Guangzhou Medical University 201721007High-level university construction project of Guangzhou Medical University 20182737IVATS National key R&D Program 2017YFC0112704IVATS National key R&D Program 2017YFC0907903Key Laboratory on Development and Application of Rural Renewable Energy (CN) 2011B090400589Key Project of Guangzhou Scientific Research Project 201804020030National Key R&D Program of China 2016YFC0905400
6 · The paper itself

Abstract

backgroundSince little consensus has been reached on whether milder reduction in forced expiratory volume in 1 s (FEV

methodsWe conducted a comprehensive search from PubMed, Medline, EMBASE, and Cochrane Library databases as of February 2020. MR analysis was performed using summary data obtained from two large consortia [International Lung Cancer Consortium (ILCCO) and Neale Lab] to assess the possible causality between FEV

resultsEight studies involving 88,743 cases were included. The incidence of lung cancer increased with decreasing FEV

conclusionFEV

Indexed as

Genetic Predisposition to DiseaseMendelian Randomization AnalysisPolymorphism, Single NucleotideCohort StudiesGenome-Wide Association StudyHumansIncidenceLungLung NeoplasmsMeta-Analysis as TopicRisk FactorsFEV1Lung cancerMendelian randomizationMeta-analysis

Identifiers

PMID34318357
PMCPMC11802027

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.