Evidence map›Paper›PMID 34318236›Full record

ArticleJTCVS techniques2021

The role of diffuse correlation spectroscopy and frequency-domain near-infrared spectroscopy in monitoring cerebral hemodynamics during hypothermic circulatory arrests.

Alexander I Zavriyev, Kutlu Kaya, Parisa Farzam, Parya Y Farzam, John Sunwoo, Arminder S Jassar, Thoralf M Sundt, Stefan A Carp, Maria Angela Franceschini, Jason Z Qu

Open access · goldAbstract read
In one paragraph

Article in JTCVS techniques, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

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  14. Usefulness of Cerebral Oximetry in TBI by NIRS.Journal of clinical medicine · 2021
    Review
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  19. Pathlength-selective, interferometric diffuse correlation spectroscopy.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Alexander I ZavriyevDepartment of Radiology, Optics at Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Kutlu KayaDepartment of Radiology, Optics at Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Parisa FarzamDepartment of Radiology, Optics at Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Parya Y FarzamDepartment of Radiology, Optics at Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
John SunwooDepartment of Radiology, Optics at Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Arminder S JassarDivision of Cardiac Surgery, Corrigan Minehan Heart Center, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Thoralf M SundtDivision of Cardiac Surgery, Corrigan Minehan Heart Center, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Stefan A CarpDepartment of Radiology, Optics at Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Maria Angela FranceschiniDepartment of Radiology, Optics at Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Jason Z QuDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Massachusetts General Hospital · USHarvard University · USAthinoula A. Martinos Center for Biomedical Imaging · US

Funding

Training Program in Biomedical Imaging and Information SciencesT32EB009384 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI GEE, JAMES C, IVES, ZACHARY · 2009 to 2023
$4.0M
Optical Monitoring of Cerebral Oxygenation in InfantsR01HD042908 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI FRANCESCHINI, MARIA ANGELA · 2002 to 2012
$3.9M
DCS cerebral blood flow monitor for extreme low-birth-weight infantsR01HD091067 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI EL-DIB, MOHAMED, FRANCESCHINI, MARIA ANGELA · 2018 to 2022
$3.3M
Non-invasive monitoring of brain health during cardio-pulmonary bypassR01NS100750 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CARP, STEFAN ALEXANDRU · 2018 to 2022
$2.9M
NIRS-DCS for monitoring anesthesia and surgical manipulations of cerebral oxygen deliveryR01GM116177 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI FRANCESCHINI, MARIA ANGELA · 2016 to 2019
$1.6M
NIBIB NIH HHS T32 EB009384NICHD NIH HHS R01 HD091067NIGMS NIH HHS R01 GM116177NINDS NIH HHS R01 NS100750
6 · The paper itself

Abstract

objectivesReal-time noninvasive monitoring of cerebral blood flow (CBF) during surgery is key to reducing mortality rates associated with adult cardiac surgeries requiring hypothermic circulatory arrest (HCA). We explored a method to monitor cerebral blood flow during different brain protection techniques using diffuse correlation spectroscopy (DCS), a noninvasive optical technique which, combined with frequency-domain near-infrared spectroscopy (FDNIRS), also provides a measure of oxygen metabolism.

methodsWe used DCS in combination with FDNIRS to simultaneously measure hemoglobin oxygen saturation (SO

resultsOur measurements revealed that a negligible amount of blood is delivered to the cerebral cortex during HCA with retrograde cerebral perfusion, indistinguishable from HCA-only cases (median CBF

conclusionsFDNIRS-DCS is able to detect changes in CBF

Indexed as

ACP, antegrade cerebral perfusionantegrade cerebral perfusionbrain imagingCBFi, cerebral blood flow (index)cerebral blood flowCMRO2i, cerebral metabolic rate of oxygen (index)CPB, cardiopulmonary bypassDCS, diffuse correlation spectroscopydiffuse correlation spectroscopyEEG, electroencephalographyFDNIRS, frequency-domain near-infrared spectroscopyHCA, hypothermic circulatory arresthypothermic circulatory arrestnear-infrared spectroscopyNIRS, near-infrared spectroscopyRCP, retrograde cerebral perfusionretrograde cerebral perfusionrSO2, regional oxygen saturationSO2, hemoglobin oxygen saturationTCD, transcranial Doppler ultrasound

Identifiers

PMID34318236
PMCPMC8311503
OpenAlexW3125676872

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.