Evidence map›Paper›PMID 34317961›Full record

ArticleJTCVS techniques2020

Finite element modeling to predict procedural success of thoracic endovascular aortic repair in type A aortic dissection.

Xun Yuan, Xiaoxin Kan, Xiao Yun Xu, Christoph A Nienaber

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JTCVS techniques, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04958083 (4D Motion of the Aorta in the Chest and Simulated Wall Stress Distribution in Relation to Aortic Events), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04958083 naunknown statusnot on this mapstarted 2021, after this paper: background citation

4D Motion of the Aorta in the Chest and Simulated Wall Stress Distribution in Relation to Aortic Events

TypeinterventionalSponsorRoyal Brompton & Harefield NHS Foundation TrustRan2021 to 2023Enrolled30ConditionsAortic DissectionArmsmultiphase ECG-gated contrast-enhanced CT
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Current Understanding of Aortic Dissection.Life (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xun YuanCardiology and Aortic Centre, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom.
Xiaoxin KanDepartment of Chemical Engineering, Imperial College London, London, United Kingdom.
Xiao Yun XuDepartment of Chemical Engineering, Imperial College London, London, United Kingdom.
Christoph A NienaberCardiology and Aortic Centre, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom.
Imperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThoracic endovascular aortic repair (TEVAR) is recommended for type B aortic dissection and recently has even been used in selected cases of proximal (Stanford type A) aortic dissections in scenarios of prohibitive surgical risk. However, mechanical interactions between the native aorta and stent-graft are poorly understood, as some cases ended in failure. The aim of this study is to explore and better understand biomechanical changes after TEVAR and predict the result via virtual stenting.

methodsA case of type A aortic dissection was considered inoperable and selected for TEVAR. The procedure failed due to stent-graft migration even with precise deployment. A novel patient-specific virtual stent-graft deployment model based on finite element method was employed to analyze TEVAR-induced changes under such conditions. Two landing positions were simulated to investigate the reason for stent-graft migration immediately after TEVAR and explore options for optimization.

resultsSimulation of the actual procedure revealed that the proximal bare metal stent pushed the lamella into the false lumen and led to further stent-graft migration during the launch phase. An alternative landing position has reduced the local deformation of the dissection lamella and avoided stent-graft migration. Higher maximum principal stress (>20 KPa) was found on the lamella with deployment at the actual position, while the alternative strategy would have reduced the stress to <5 KPa.

conclusionsVirtual stent-graft deployment simulation based on finite element model could be helpful to both predict outcomes of TEVAR and better plan future endovascular procedures.

Indexed as

CT, computed tomographyECG, electrocardiogramfinite element analysisTEVARTEVAR, thoracic endovascular aortic repairtype A aortic dissectionvirtual stent-graft deployment

Identifiers

PMID34317961
PMCPMC8307501
OpenAlexW3093281778

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.