Evidence map›Paper›PMID 34317916›Full record

ArticleJTCVS techniques2020

Constant-rate intravenous infusion of indocyanine green leading to high fluorescence intensity in infrared thoracoscopic segmentectomy.

Noriyuki Misaki, Kiichi Tatakawa, Sung Soo Chang, Tetsuhiko Go, Hiroyasu Yokomise

Open access · goldAbstract read
In one paragraph

Article in JTCVS techniques, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Noriyuki MisakiDepartment of General Thoracic Surgery, Takamatsu Municipal Hospital, Takamatsu City, Kagawa Prefecture, Japan.
Kiichi TatakawaDepartment of General Thoracic Surgery, Takamatsu Municipal Hospital, Takamatsu City, Kagawa Prefecture, Japan.
Sung Soo ChangDepartment of General Thoracic Breast and Endocrinological Surgery, Kagawa University, Takamatsu City, Kagawa Prefecture, Japan.
Tetsuhiko GoDepartment of General Thoracic Breast and Endocrinological Surgery, Kagawa University, Takamatsu City, Kagawa Prefecture, Japan.
Hiroyasu YokomiseDepartment of General Thoracic Breast and Endocrinological Surgery, Kagawa University, Takamatsu City, Kagawa Prefecture, Japan.
Kagawa University · JPNational Hospital Organization Takamatsu Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe purpose of this study was to determine whether or not fluorescence could be increased by administering indocyanine green at a constant rate, thus stabilizing its blood concentration.

methodsIn 20 consecutive patients undergoing segmentectomy, the dominant pulmonary arteries were ligated, blocking blood in the target segment. Fluorescence intensity was then observed using different indocyanine green administration methods under infrared thoracoscopy. Intravenous administration of indocyanine green, via a syringe pump at a rate of 12.5 mg/min, was defined as the constant rate group. The bolus group was defined by a 5-mg indocyanine green rapid intravenous injection. The fluorescence intensity was compared at the time of maximum fluorescence and 2 minutes after fluorescence initiation.

resultsAt maximum staining, the fluorescence intensity of the normal blood flow area was brighter in the constant rate group (median, 184.2; interquartile range, 170.2-200.1) compared with the bolus group (median, 122.3; interquartile range, 87.3-144.7;

conclusionsThe constant rate method showed brighter and better fluorescence than the bolus injection, without an increase in the dose. The contrast between adjacent segments was clear, facilitating the differentiation of the areas.

Indexed as

2M, 2 minutes after the injectionconstantfluorescenceICG, indocyanine greenindocyanine greeninfrared thoracoscopyMax, maximumsegmentectomy

Identifiers

PMID34317916
PMCPMC8302929
OpenAlexW3024973244

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.