Evidence map›Paper›PMID 34317680›Full record

ArticleJACC. Case reports2021

Interferon-β-Induced Pulmonary Arterial Hypertension: Approach to Diagnosis and Clinical Monitoring.

Farhan Raza, Callyn Kozitza, Amy Chybowski, Kara N Goss, Theodore Berei, James Runo, Marlowe Eldridge, Naomi Chesler

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Farhan RazaDivision of Cardiology, Department of Medicine, University of Wisconsin, Madison, Wisconsin, USA.
Callyn KozitzaDepartment of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin, USA.
Amy ChybowskiDivision of Pulmonary and Critical Care, Department of Medicine and Pediatrics, University of Wisconsin, Madison, Wisconsin, USA.
Kara N GossDivision of Pulmonary and Critical Care, Department of Medicine and Pediatrics, University of Wisconsin, Madison, Wisconsin, USA.
Theodore BereiDepartment of Pharmacy, University of Wisconsin, Madison, Wisconsin, USA.
James RunoDivision of Pulmonary and Critical Care, Department of Medicine and Pediatrics, University of Wisconsin, Madison, Wisconsin, USA.
Marlowe EldridgeDepartment of Pediatrics. University of Wisconsin, Madison, Wisconsin, USA.
Naomi CheslerDepartment of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin, USA.
University of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 48-year-old woman who had been receiving long-term interferon-β for 8 years for multiple sclerosis developed drug-induced World Health Organization group I pulmonary arterial hypertension. Triple therapy for pulmonary arterial hypertension and suspension of interferon-β led to improvement from a high-risk to low-risk state and improvement in exercise hemodynamics, including vascular distensibility, and right ventricle-pulmonary artery coupling. (

Indexed as

6MWD, 6-min walk distanceBNP, B-type natriuretic peptideBP, blood pressureCMR, cardiac magnetic resonanceCPET, cardiopulmonary exercise testDlco, diffusion capacity of carbon monoxideET, endothelinexerciseIFN, interferonMS, multiple sclerosisNYHA, New York Heart AssociationPAH, pulmonary arterial hypertensionPA, pulmonary arterialpulmonary hypertensionRHC, right-sided heart catheterizationright ventricleRV, right ventricular

Identifiers

PMID34317680
PMCPMC8311374
OpenAlexW3155468327

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.