Evidence map›Paper›PMID 34317115›Full record

ArticleJACC. Case reports2020

Lenalidomide-Induced Myocarditis, Rare But Possibly Fatal Toxicity of a Commonly Used Immunotherapy.

Robin Jacob, Paolo Strati, Nicolas Palaskas, Juan C Lopez-Mattei, Konstantinos Marmagkiolis, L Maximilian Buja, Anita Deswal, Cezar Iliescu

Open access · goldAbstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Constrictive Pericarditis as a Post-Cardiac Surgery Complication.The American journal of case reports · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Robin JacobDepartment of Cardiology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Paolo StratiDepartment of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Nicolas PalaskasDepartment of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Juan C Lopez-MatteiDepartment of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Konstantinos MarmagkiolisDepartment of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
L Maximilian BujaDepartment of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Anita DeswalDepartment of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Cezar IliescuDepartment of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
The University of Texas MD Anderson Cancer Center · USThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 66-year-old woman with follicular lymphoma on lenalidomide and rituximab presented with chest pain. High-sensitivity troponin T peaked at 7,566 ng/l. Cardiac biopsy revealed extensive inflammation consistent with medication-induced myocarditis. Lenalidomide was stopped with improvement in troponins and patient was initiated on high-dose corticosteroid therapy. (

Indexed as

cardio-oncologycardiotoxicityfollicular lymphomahsTnT, high-sensitivity troponin Tlenalidomidemyocarditis

Identifiers

PMID34317115
PMCPMC8299772
OpenAlexW3089982764

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.