Evidence map›Paper›PMID 34316822›Full record

ArticleJACC. Case reports2019

Corneal Clouding in a Young Woman With Low HDL Cholesterol.

Lisa R Koenig, Joshua Z Warren, Jacquelyn P Kulinski

Open access · goldAbstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lisa R KoenigWeill Cornell Medical College, New York, New York.
Joshua Z WarrenDepartment of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin.
Jacquelyn P KulinskiDepartment of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Medical College of Wisconsin · USCornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report describes the early diagnosis of lecithin cholesterol acyl transferase deficiency in a young asymptomatic woman who initially presented to ophthalmology with bilateral corneal clouding. The diagnosis was suggested by characteristic slit-lamp findings, undetectable high-density lipoprotein, and proteinuria, and it was confirmed by cardiology consultation and genetic testing. (

Indexed as

apoA1, apolipoprotein A1genetic disordersHDL, high-density lipoproteinLCAT, lecithin cholesterol acyl transferaselipid metabolism disordersmetabolic syndrome XNIH, National Institutes of Health

Identifiers

PMID34316822
PMCPMC8288582
OpenAlexW2973808882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.