Evidence map›Paper›PMID 34316727›Full record

ArticleThe Lancet. Rheumatology2021

Immediate effect of the COVID-19 pandemic on patient health, health-care use, and behaviours: results from an international survey of people with rheumatic diseases.

Jonathan S Hausmann, Kevin Kennedy, Julia F Simard, Jean W Liew, Jeffrey A Sparks, Tarin T Moni, Carly Harrison, Maggie J Larché, Mitchell Levine, Sebastian E Sattui and 23 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Lancet. Rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. JAK inhibitors and COVID-19.Journal for immunotherapy of cancer · 2022
    Pooled it
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  13. Functional and psychosocial impact of COVID-19 pandemic on rheumatic patients' quality of life in Saudi Arabia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 20 institutions in 7 countries.

Jonathan S HausmannDivision of Rheumatology and Clinical Immunology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Kevin KennedyDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Julia F SimardDepartment of Epidemiology and Population Health, and Division of Immunology and Rheumatology, Department of Medicine, Stanford School of Medicine, Stanford, CA, USA.
Jean W LiewDepartment of Medicine, Boston University School of Medicine, Boston, MA, USA.
Jeffrey A SparksDivision of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Tarin T MoniDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada.
Carly HarrisonLupusChat, New York, NY, USA.
Maggie J LarchéDivisions of Rheumatology/Clinical Immunology and Allergy, McMaster University, Hamilton, ON, Canada.
Mitchell LevineDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Sebastian E SattuiDivision of Rheumatology, Department of Medicine, Hospital for Special Surgery, New York, NY, USA.
Teresa SemaluluDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Gary FosterDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Salman SurangiwalaSchool of Medicine, Queen's University, Kingston, ON, Canada.
Lehana ThabaneDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Richard P BeesleyJuvenile Arthritis Research, Tonbridge, UK.
Karen L DurrantAutoinflammatory Alliance, San Francisco, CA, USA.
Elsa F MateusPortuguese League Against Rheumatic Diseases, Comprehensive Health Research Centre, Lisbon, Portugal.
Serena MingollaItalian National Association of People with Rheumatic and Rare Diseases, Brindisi, Italy.
Michal NudelThe Israeli association for RMDs patients "Mifrakim Tz'eirim", Haifa, Israel.
Candace A PalmerleeRelapsing Polychondritis Foundation, International Relapsing Polychondritis Research Network, Walnut Creek, CA, USA.
Dawn P RichardsCanadian Arthritis Patient Alliance, Toronto, ON, Canada.
David F L LiewDepartment of Rheumatology, Austin Health, Heidelberg, Australia.
Catherine L HillRheumatology Unit, The Queen Elizabeth Hospital, Woodville South, Australia.
Suleman BhanaCrystal Run Healthcare, Middletown, NY, USA.
Wendy CostelloIrish Children's Arthritis Network, Tipperary, Ireland.
Rebecca GraingerDepartment of Medicine, University of Otago, Wellington, New Zealand.
Pedro M MachadoCentre for Rheumatology and Department of Neuromuscular Diseases, University College London, London, UK.
Philip C RobinsonFaculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
Paul SufkaHealthPartners, St Paul, MN, USA.
Zachary S WallaceDivision of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Jinoos YazdanyDivision of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Emily SirotichDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
COVID-19 Global Rheumatology Alliance
McMaster University · CACanadian Arthritis Patient Alliance · CAImpact · CAHarvard University · USHealthPartners · USUniversity of California, San Francisco · USAustin Health · AUBoston Children's Hospital · USBoston University · USCrystal Run Healthcare · USDigital Research Alliance of CanadaHospital for Special Surgery · USLupusChat · USNational Institute for Health Research · GBPortuguese League Against Epilepsy · PTStanford Medicine · USUniversity of Queensland · AUBrigham and Women's Hospital · USLondon North West Healthcare NHS Trust · GBNational Health Service · GB

Funding

RESOURCE-BASED CENTER FOR THE ADVANCEMENT OF PRECISION MEDICINE IN RHEUMATOLOGYP30AR070155 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mary C Nakamura · 2016 to 2026
$8.2M
Computational methods using electronic health records and registry data to detect and predict clinical outcomes in rheumatic diseaseK01AR075085 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GIANFRANCESCO, MILENA ANNE · 2019 to 2022
$458k
NIAMS NIH HHS K01 AR075085NIAMS NIH HHS P30 AR070155
6 · The paper itself

Abstract

backgroundThe impact and consequences of the COVID-19 pandemic on people with rheumatic disease are unclear. We developed the COVID-19 Global Rheumatology Alliance Patient Experience Survey to assess the effects of the COVID-19 pandemic on people with rheumatic disease worldwide.

methodsSurvey questions were developed by key stakeholder groups and disseminated worldwide through social media, websites, and patient support organisations. Questions included demographics, rheumatic disease diagnosis, COVID-19 diagnosis, adoption of protective behaviours to mitigate COVID-19 exposure, medication access and changes, health-care access and communication with rheumatologists, and changes in employment or schooling. Adults age 18 years and older with inflammatory or autoimmune rheumatic diseases were eligible for inclusion. We included participants with and without a COVID-19 diagnosis. We excluded participants reporting only non-inflammatory rheumatic diseases such as fibromyalgia or osteoarthritis.

findings12 117 responses to the survey were received between April 3 and May 8, 2020, and of these, 10 407 respondents had included appropriate age data. We included complete responses from 9300 adults with rheumatic disease (mean age 46·1 years; 8375 [90·1%] women, 893 [9·6%] men, and 32 [0·3%] participants who identified as non-binary). 6273 (67·5%) of respondents identified as White, 1565 (16·8%) as Latin American, 198 (2·1%) as Black, 190 (2·0%) as Asian, and 42 (0·5%) as Native American or Aboriginal or First Nation. The most common rheumatic disease diagnoses included rheumatoid arthritis (3636 [39·1%] of 9300), systemic lupus erythematosus (2882 [31·0%]), and Sjögren's syndrome (1290 [13·9%]). Most respondents (6921 [82·0%] of 8441) continued their antirheumatic medications as prescribed. Almost all (9266 [99·7%] of 9297) respondents adopted protective behaviours to limit SARS-CoV-2 exposure. A change in employment status occurred in 2524 (27·1%) of 9300) of respondents, with a 13·6% decrease in the number in full-time employment (from 4066 to 3514).

interpretationPeople with rheumatic disease maintained therapy and followed public health advice to mitigate the risks of COVID-19. Substantial employment status changes occurred, with potential implications for health-care access, medication affordability, mental health, and rheumatic disease activity.

fundingAmerican College of Rheumatology.

Identifiers

PMID34316727
PMCPMC8298011
OpenAlexW3186673974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.