Evidence map›Paper›PMID 34316662›Full record

ArticleClinical parkinsonism & related disorders2021

Non-motor features of cervical dystonia: Cognition, social cognition, psychological distress and quality of life.

Ruth Monaghan, Clodagh Cogley, Tom Burke, Derval McCormack, Sean O'Riordan, Ihedinachi Ndukwe, Michael Hutchinson, Niall Pender, Fiadhnait O'Keeffe

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical parkinsonism & related disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Psychosocial and body image alterations associated with focal dystonia.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Article
  4. Article
  5. Social cognition in idiopathic focal dystonia: preliminary evidence on its relationship with cognitive and affective-behavioral functioning.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Social cognition in cervical dystonia.Clinical parkinsonism & related disorders · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ruth MonaghanSt Vincent's University Hospital, Dublin, Ireland.
Clodagh CogleySt Vincent's University Hospital, Dublin, Ireland.
Tom BurkeDepartment of Psychology, Beaumont Hospital, Dublin 9, Ireland.
Derval McCormackSt Vincent's University Hospital, Dublin, Ireland.
Sean O'RiordanSt Vincent's University Hospital, Dublin, Ireland.
Ihedinachi NdukweSt Vincent's University Hospital, Dublin, Ireland.
Michael HutchinsonSt Vincent's University Hospital, Dublin, Ireland.
Niall PenderDepartment of Psychology, Beaumont Hospital, Dublin 9, Ireland.
Fiadhnait O'KeeffeSt Vincent's University Hospital, Dublin, Ireland.
University College Dublin · IERoyal College of Surgeons in Ireland · IESt. Vincent's University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNon-motor features of cervical dystonia (CD) have been identified, including depression, anxiety, and neuropsychological deficits. The aims were: to provide a clinical neuropsychological profile of CD patients with specific focus on social cognition; assess levels of psychological distress; and investigate the relationship between non-motor features of CD, including cognitive functioning, psychological distress, CD severity, pain, and health-related quality of life (HR-QoL).

methodsA multi-domain neuropsychological assessment battery was administered to 46 participants with CD, examining cognitive and social cognitive domains. Clinical data on dystonia severity, pain, psychological distress and HR-QoL were collected.

resultsThe majority of participants with CD performed within the average range across most tests of cognition. Scores were significantly lower than standardized norms in social cognition, processing speed, and aspects of memory. High levels of anxiety (Hospital Anxiety and Depression Scale [HADS-A] ≥ 11, 30%) and depression (HADS-D ≥ 11; 29%) were observed. Psychological distress, CD severity, pain and HR-QoL were not significantly associated with neuropsychological functioning after controlling for multiple comparisons. Low HR-QoL was associated with higher levels of pain and psychological distress, but not severity of motor symptoms.

conclusionResults indicate that psychological distress and deficits in cognitive and social cognitive functioning are likely distinct features of CD. While motor symptoms do not appear to impact HR-QoL, pain and psychological distress were associated with low HR-QoL. Findings highlight the importance of addressing non-motor symptoms in the treatment of CD.

Indexed as

Cervical dystoniaNeuropsychological testingNon-motor symptomsPsychological distressSocial cognition

Identifiers

PMID34316662
PMCPMC8299967
OpenAlexW3110748807

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.